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DHODH Antibody (PA5-89141) in IHC (P)
Immunohistochemistry analysis of DHODH in paraffin-embedded human stomach. Samples were incubated with DHODH Polyclonal antibody (Product # PA5-89141) using a dilution of 1:200 (40x lens). Perform microwave antigen retrieval with 10 mM PBS buffer pH 7.2 before commencing with IHC staining protocol.
产品信息
PA5-89141
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 116-395 of human DHODH (NP_0013522)
偶联物
Unconjugated
形式
Liquid
浓度
0.82 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2805383
产品详细信息
Immunogen sequence: EIGSVTPKPQ EGNPRPRVFR LPEDQAVINR YGFNSHGLSV VEHRLRARQQ KQAKLTEDGL PLGVNLGKNK TSVDAAEDYA EGVRVLGPLA DYLVVNVSSP NTAGLRSLQG KAELRRLLTK VLQERDGLRR VHRPAVLVKI APDLTSQDKE DIASVVKELG IDGLIVTNTT VSRPAGLQGA LRSETGGLSG KPLRDLSTQT IREMYALTQG RVPIIGVGGV SSGQDALEKI RAGASLVQLY TALTFWGPPV VGKVKRELEA LLKEQGFGGV TDAIGADHRR; Positive Samples: HL-60, SW620, HepG2, Mouse heart, Mouse spleen, Mouse kidney, Rat heart, Rat kidney; Cellular Location: Mitochondrion inner membrane, Single-pass membrane protein
靶标信息
The protein encoded by this gene catalyzes the fourth enzymatic step, the ubiquinone-mediated oxidation of dihydroorotate to orotate, in de novo pyrimidine biosynthesis. This protein is a mitochondrial protein located on the outer surface of the inner mitochondrial membrane. [provided by RefSeq, Jul 2008].
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: DHOdehase; Dihydroorotate dehydrogenase (quinone), mitochondrial; dihydroorotate dehydrogenase, mitochondrial; Dihydroorotate oxidase; human complement of yeast URA1
基因别名: 2810417D19Rik; AI834883; DHOdehase; DHODH; POADS; URA1
UniProt ID: (Human) Q02127, (Rat) Q63707, (Mouse) O35435
Entrez Gene ID: (Human) 1723, (Rat) 65156, (Mouse) 56749
'de novo' pyrimidine nucleobase biosynthetic process
female pregnancy
lactation
response to caffeine
response to drug
response to starvation
positive regulation of apoptotic process
'de novo' UMP biosynthetic process
pyrimidine nucleoside biosynthetic process
oxidation-reduction process
regulation of mitochondrial fission
response to organic cyclic compound
pyrimidine nucleotide biosynthetic process
UMP biosynthetic process
