Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
图: 1 / 2
DLL1 Antibody (H00028514-D01P) in WB
Western Blot analysis of DLL1 expression in transfected 293T cell line (H00028514-T01) by DLL1 MaxPab polyclonal antibody.
Lane 1: DLL1 transfected lysate(79.53 KDa).
Lane 2: Non-transfected lysate.
Lane 1: DLL1 transfected lysate(79.53 KDa).
Lane 2: Non-transfected lysate.
产品信息
H00028514-D01P
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
DLL1 (NP_005609.3, 1 a.a. approximately 723 a.a) full-length human protein.
偶联物
形式
Liquid
浓度
See Label
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Sequence of this protein is as follows: MGSRCALALA VLSALLCQVW SSGVFELKLQ EFVNKKGLLG NRNCCRGGAG PPPCACRTFF RVCLKHYQAS VSPEPPCTYG SAVTPVLGVD SFSLPDGGGA DSAFSNPIRF PFGFTWPGTF SLIIEALHTD SPDDLATENP ERLISRLATQ RHLTVGEEWS QDLHSSGRTD LKYSYRFVCD EHYYGEGCSV FCRPRDDAFG HFTCGERGEK VCNPGWKGPY CTEPICLPGC DEQHGFCDKP GECKCRVGWQ GRYCDECIRY PGCLHGTCQQ PWQCNCQEGW GGLFCNQDLN YCTHHKPCKN GATCTNTGQG SYTCSCRPGY TGATCELGID ECDPSPCKNG GSCTDLENSY SCTCPPGFYG KICELSAMTC ADGPCFNGGR CSDSPDGGYS CRCPVGYSGF NCEKKIDYCS SSPCSNGAKC VDLGDAYLCR CQAGFSGRHC DDNVDDCASS PCANGGTCRD GVNDFSCTCP PGYTGRNCSA PVSRCEHAPC HNGATCHERG HRYVCECARG YGGPNCQFLL PELPPGPAVV DLTEKLEGQG GPFPWVAVCA GVILVLMLLL GCAAVVVCVR LRLQKHRPPA DPCRGETETM NNLANCQREK DISVSIIGAT QIKNTNKKAD FHGDHSADKN GFKARYPAVD YNLVQDLKGD DTAVRDAHSK RDTKCQPQGS SGEEKGTPTT LRGGEASERK RPDSGCSTSK DTKYQSVYVI SEEKDECVIA TEV
靶标信息
Delta-like protein 1 (DLL1) is a transmembrane protein characterized by epidermal growth factor (EGF)-like repeats. It is a ligand for Notch receptor. It blocks the differentiation of progenitor cells into the B-cell lineage while promoting the emergence of a population of cells with the characteristics of a T-cell/NK-cell precursor.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
篇参考文献 (0)
您是否在文献中引用过该产品？请点击下方按钮邮件告知我们。
生物信息学
蛋白别名: Delta-like protein 1; Delta1; Drosophila Delta homolog 1; H-Delta-1; OTTHUMP00000017690
基因别名: Delta; DELTA1; DL1; DLL1; UNQ146/PRO172
UniProt ID: (Human) O00548
Entrez Gene ID: (Human) 28514
cell fate determination
somitogenesis
somite specification
heart looping
marginal zone B cell differentiation
type B pancreatic cell development
Notch signaling pathway
Notch receptor processing
determination of left/right symmetry
compartment pattern specification
regulation of blood pressure
positive regulation of cell proliferation
negative regulation of cell proliferation
proximal/distal pattern formation
astrocyte development
regulation of somitogenesis
spinal cord development
cerebellar molecular layer formation
cerebellar Purkinje cell layer structural organization
hemopoiesis
cell differentiation
regulation of cell adhesion
negative regulation of epithelial cell differentiation
negative regulation of interleukin-10 production
negative regulation of glial cell apoptotic process
organ growth
regulation of growth
negative regulation of cell differentiation
negative regulation of epidermal cell differentiation
negative regulation of auditory receptor cell differentiation
negative regulation of myeloid cell differentiation
negative regulation of myoblast differentiation
negative regulation of neuron differentiation
positive regulation of Notch signaling pathway
positive regulation of endocytosis
positive regulation of transcription from RNA polymerase II promoter
lateral inhibition
skeletal muscle tissue growth
regulation of skeletal muscle tissue growth
positive regulation of skeletal muscle tissue growth
neuron fate specification
inner ear development
regulation of neurogenesis
regulation of cell division
retina development in camera-type eye
retina morphogenesis in camera-type eye
Notch signaling pathway involved in arterial endothelial cell fate commitment
left/right axis specification
nephron development
proximal tubule development
loop of Henle development
clathrin-mediated endocytosis
endothelial tip cell fate specification
neuronal stem cell population maintenance
skin epidermis development
regulation of vascular endothelial growth factor signaling pathway
positive regulation of sprouting angiogenesis
regulation of energy homeostasis
