Target of Interest
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产品信息
PA5-69058
产品规格
种属反应
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
synthetic peptide directed towards the middle region of human DLX1 (aa 22-44)
偶联物
Unconjugated
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Affinity chromatography
保存液
PBS with 2% sucrose
内含物
0.09% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2690212
产品详细信息
This target displays homology in the following species: Cow: 93%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 79%
靶标信息
This gene encodes a member of a homeobox transcription factor gene family similiar to the Drosophila distal-less gene. The encoded protein is localized to the nucleus where it may function as a transcriptional regulator of signals from multiple TGF-beta superfamily members. The encoded protein may play a role in the control of craniofacial patterning and the differentiation and survival of inhibitory neurons in the forebrain. This gene is located in a tail-to-tail configuration with another member of the family on the long arm of chromosome 2. Alternatively spliced transcript variants encoding different isoforms have been described.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: homeobox Dlx1; homeobox protein DLX-1
Entrez Gene ID: (Rat) 296500
negative regulation of transcription from RNA polymerase II promoter
regulation of transcription from RNA polymerase II promoter
multicellular organism development
proximal/distal pattern formation
subpallium development
hippocampus development
forebrain neuron differentiation
regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment
cerebral cortex GABAergic interneuron differentiation
cerebral cortex GABAergic interneuron fate commitment
cell differentiation
odontogenesis of dentin-containing tooth
negative regulation of neuron apoptotic process
negative regulation of Notch signaling pathway
embryonic skeletal system development
negative regulation of oligodendrocyte differentiation
