Abnova

DLX2 Monoclonal Antibody (2C8)

查看其他18个DLX2抗体

抗体检测数据 (3)

DLX2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

DLX2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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DLX2 Antibody (H00001746-M06) in IHC (P)

Immunoperoxidase of monoclonal antibody to DLX2 on formalin-fixed paraffin-embedded human esophagus. Antibody concentration is 1 µg/mL.

DLX2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

DLX2 Antibody in Western Blot (WB)

DLX2 Antibody in ELISA (ELISA)

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DLX2 Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — Immunoperoxidase of monoclonal antibody to DLX2 on formalin-fixed paraffin-embedded human esophagus. Antibody concentration is 1 µg/mL.

DLX2 Antibody in Western Blot (WB) — DLX2 monoclonal antibody (M06), clone 2C8 Western Blot analysis of DLX2 expression in NIH/3T3 (Cat # L018V1).

DLX2 Antibody in ELISA (ELISA) — Detection limit for recombinant GST tagged DLX2 is approximately 1 ng/mL as a capture antibody.

产品信息

H00001746-M06

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1-5 µg/mL

-

免疫组化（石蜡） (IHC (P))

1 µg/mL

-

酶联免疫吸附实验 (ELISA)

1 ng/mL

-

产品规格

种属反应

Human, Mouse

宿主/亚型

Mouse / IgG2a, kappa

分类

Monoclonal

类型

Antibody

克隆号

2C8

抗原

DLX2 (NP_004396.1, 1 a.a. approximately 110 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

See Label

纯化类型

Affinity chromatography

保存液

PBS, pH 7.4

内含物

no preservative

保存条件

-20° C, Avoid Freeze/Thaw Cycles

运输条件

Ambient (domestic); Wet ice (international)

产品详细信息

Sequence of this protein is as follows: MTGVFDSLVA DMHSTQIAAS STYHQHQQPP SGGGAGPGGN SSSSSSLHKP QESPTLPVST ATDSSYYTNQ QHPAGGGGGG GSPYAHMGSY QYQASGLNNV PYSAKSSYDL

靶标信息

Many vertebrate homeo box-containing genes have been identified on the basis of their sequence similarity with Drosophila developmental genes. Members of the Dlx gene family contain a homeobox that is related to that of Distal-less (Dll), a gene expressed in the head and limbs of the developing fruit fly. The Distal-less (Dlx) family of genes comprises at least 6 different members, DLX1-DLX6. The DLX proteins are postulated to play a role in forebrain and craniofacial development. This gene is located in a tail-to-tail configuration with another member of the gene family on the long arm of chromosome 2.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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引用该产品

生物信息学

蛋白别名: DII A; distal-less homeo box 2; Homeobox protein DLX-2; Homeobox protein TES-1

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基因别名: AW121999; Dlx-2; DLX2; TES-1; TES1

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UniProt ID: (Human) Q07687, (Mouse) P40764

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Entrez Gene ID: (Human) 1746, (Mouse) 13392

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RNA polymerase II regulatory region sequence-specific DNA binding transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding chromatin binding transcription factor activity, sequence-specific DNA binding single-stranded RNA binding protein binding DNA binding sequence-specific DNA binding homeodomain transcription factor

参与通路

negative regulation of transcription from RNA polymerase II promoter transcription from RNA polymerase II promoter brain development proximal/distal pattern formation subpallium development hippocampus development olfactory bulb development regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment cerebral cortex GABAergic interneuron fate commitment odontogenesis of dentin-containing tooth negative regulation of Notch signaling pathway positive regulation of transcription from RNA polymerase II promoter embryonic cranial skeleton morphogenesis negative regulation of oligodendrocyte differentiation branching morphogenesis of a nerve cartilage development regulation of transcription, DNA-templated regulation of transcription from RNA polymerase II promoter multicellular organism development forebrain neuron differentiation cerebral cortex GABAergic interneuron differentiation cell differentiation embryonic skeletal system development