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DMC1 Antibody (PA5-21472) in IHC (P)
DMC1 Polyclonal Antibody detects DMC1 protein at nucleolus on mouse testis by immunohistochemical analysis. Sample: Paraffin-embedded mouse testis. DMC1 Polyclonal Antibody (Product # PA5-21472) dilution: 1:500. Antigen Retrieval: EDTA based buffer, pH 8.0, 15 min.
产品信息
PA5-21472
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse
已发表种属
Sea urchin
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fragment corresponding to a region within amino acids 1 and 206 of DMC1 (Uniprot ID#Q14565)
偶联物
形式
Liquid
浓度
0.9 mg/mL
纯化类型
Antigen affinity chromatography
保存液
0.1M tris glycine, pH 7, with 20% glycerol
内含物
0.01% thimerosal
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_11152849
产品详细信息
Recommended positive controls: 293T, HeLa, Molt-4, Raji, mouse testis.
Predicted reactivity: Mouse (94%), Rat (95%), Zebrafish (83%), Japanese Medaka (84%), Bovine (98%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
DMC1 is essential for meiotic homologous recombination. Genetic recombination in meiosis plays an important role in generating diversity of genetic information. The product of this protein is structurally and evolutionary related to the products of the yeast RAD51 and E. coli RecA genes.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: disrupted meiotic cDNA 1 homolog; disrupted meiotic cDNA1, yeast, homolog of; DMC 1; DMC1 dosage suppressor of mck1 homolog, meiosis-specific homologous recombination; DMC1 homologue; HsLim15; Meiotic recombination protein DMC1/LIM15 homolog; MGC150472; MGC150473; RP1-199H16.4
基因别名: dJ199H16.1; DMC1; DMC1H; LIM15; Mei11; sgdp
UniProt ID: (Human) Q14565, (Mouse) Q61880
Entrez Gene ID: (Human) 11144, (Mouse) 13404
DNA recombinase assembly
ovarian follicle development
oocyte maturation
mitotic recombination
meiotic nuclear division
synapsis
reciprocal meiotic recombination
male meiosis I
spermatogenesis
spermatid development
female gamete generation
response to ionizing radiation
strand invasion
chromosome organization involved in meiotic cell cycle
DNA metabolic process
DNA repair
cell cycle
gamete generation
meiotic cell cycle
