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Immunogen sequence: EDLSQLTRSM VKFPGGTPGR WEKIAHELGR SVTDVTTKAK QLKDSVTCSP GMVRLSELKS TVQNSRPIKT ATTLPDDMIT QREDAEGVAA EEEQEGDSGE QETGATDARP RRRKPARLLE ATAKPEPEEK SRAKRQKDFD IAEQNESS
Highest antigen sequence identity to the following orthologs: Mouse - 77%, Rat - 75%.
The p95 gene (identical to NBS1 and nibrin) is a member of the hMre11/hRad50 double-strand break complex. This protein complex has been implicated in Nijmegen breakage syndrome, an autosomal recessive disorder marked by increased cancer incidence, cell cycle checkpoint deficits, and ionizing radiation sensitivity, thus revealing a direct molecular link between double-strand break repair and cell cycle checkpoint functions.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: DnaJ (Hsp40) homolog, subfamily C, member 1; DnaJ homolog subfamily C member 1; DnaJ protein homolog MTJ1; DnaJ-like protein
基因别名: DNAJC1; DNAJL1; ERdj1; HTJ1; MTJ1
UniProt ID: (Human) Q96KC8
Entrez Gene ID: (Human) 64215
分子生物学功能: chaperone