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The protein encoded by this gene is a guanine nucleotide exchange factor (GEF) that plays a role in axon formation and neuronal polarization. The encoded protein displays GEF activity toward RAC1 and RAC3 Rho small GTPases but not toward CDC42. Several transcript variants encoding different isoforms have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Dedicator of cytokinesis protein 7
基因别名: DOCK7; EIEE23; KIAA1771; ZIR2
UniProt ID: (Human) Q96N67
Entrez Gene ID: (Human) 85440
分子生物学功能:
guanyl-nucleotide exchange factor