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The protein encoded by this gene is a member of the d4 domain family, characterized by a zinc finger-like structural motif. This protein functions as a transcription factor which is necessary for the apoptotic response following deprivation of survival factors. It likely serves a regulatory role in rapid hematopoietic cell growth and turnover. This gene is considered a candidate gene for multiple endocrine neoplasia type I, an inherited cancer syndrome involving multiple parathyroid, enteropancreatic, and pituitary tumors.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Apoptosis response zinc finger protein; BAF45D; BRG1-associated factor 45D; D4, zinc and double PHD fingers family 2; neuro-d4/requiem; Protein requiem; requiem; requiem, apoptosis response zinc finger; Zinc finger protein ubi-d4
基因别名: 2210010M07Rik; BAF45D; DPF2; REQ; ubi-d4; UBID4
UniProt ID: (Human) B4DT58, (Mouse) Q61103
Entrez Gene ID: (Human) 5977, (Rat) 361711, (Mouse) 19708
分子生物学功能: histone modifying enzyme