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As part of the MLL1/MLL complex, involved in the methylation of histone H3 at 'Lys-4', particularly trimethylation. Histone H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. May play some role in histone H3 acetylation. In a teratocarcinoma cell, plays a crucial role in retinoic acid-induced differentiation along the neural lineage, regulating gene induction and H3 'Lys-4' methylation at key developmental loci. May also play an indirect or direct role in endosomal transport.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: dosage compensation-related protein DPY30; dpy-30 histone methyltransferase complex regulatory subunit; dpy-30 homolog; Dpy-30-like protein; Dpy-30L; Protein dpy-30 homolog
基因别名: 2810410M20Rik; C87842; Cps25; DPY30; HDPY-30; Saf19
UniProt ID: (Human) Q9C005, (Mouse) Q99LT0
Entrez Gene ID: (Human) 84661, (Mouse) 66310