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Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine. Also involved the degradation of the chemotherapeutic drug 5-fluorouracil.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: DHPDHase; Dihydropyrimidine dehydrogenase [NADP(+)]; Dihydrothymine dehydrogenase; Dihydrouracil dehydrogenase; DPD
基因别名: DHP; DHPDHASE; DPD; DPYD
UniProt ID: (Human) Q12882, (Rat) O89000
Entrez Gene ID: (Human) 1806, (Rat) 81656
分子生物学功能: dehydrogenase oxidoreductase metabolite interconversion enzyme