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Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
This gene encodes the D3 subtype of the five (D1-D5) dopamine receptors. The activity of the D3 subtype receptor is mediated by G proteins which inhibit adenylyl cyclase. This receptor is localized to the limbic areas of the brain, which are associated with cognitive, emotional, and endocrine functions. Genetic variation in this gene may be associated with susceptibility to hereditary essential tremor 1. Alternative splicing of this gene results in transcript variants encoding different isoforms, although some variants may be subject to nonsense-mediated decay (NMD).
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仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: D(3) dopamine receptor; D3 receptor; D3nf; Dopamine 3 receptor; Dopamine D3 receptor; dopamine receptor 3; dopaminergic receptor D3; essential tremor 1
基因别名: D3DR; D3R; DRD3; ETM1; FET1
UniProt ID: (Human) P35462, (Rat) P19020, (Mouse) P30728
Entrez Gene ID: (Human) 1814, (Rat) 29238, (Mouse) 13490
分子生物学功能: G-protein coupled receptor