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DTX4 Antibody (PA5-49652) in IHC (P)
Immunohistochemistry analysis of DTX4 in formalin-fixed and paraffin-embedded human brain tissue. Samples were incubated with DTX4 polyclonal antibody (Product # PA5-49652) which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
产品信息
PA5-49652
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
已发表种属
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
KLH conjugated synthetic peptide between 56-83 amino acids from the N-terminal region of human DTX4.
偶联物
形式
Liquid
纯化类型
Protein A, Antigen affinity chromatography
保存液
PBS, pH 7.4
内含物
0.09% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2635106
产品详细信息
Predicted to react with mouse based on sequence homology.
靶标信息
DTX4 is a regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations. It functions as an ubiquitin ligase protein in vivo, mediating 'Lys48'-linked polyubiquitination and promoting degradation of TBK1, targeting to TBK1 requires interaction with NLRP4.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: deltex 4 homolog; deltex 4, E3 ubiquitin ligase; deltex homolog 4; Deltex4; E3 ubiquitin-protein ligase DTX4; Protein deltex-4; RING finger protein 155; RING-type E3 ubiquitin transferase DTX4
基因别名: DTX4; KIAA0937; RNF155
UniProt ID: (Human) Q9Y2E6
Entrez Gene ID: (Human) 23220
