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DYNC1I2 Antibody (PA5-22229) in IHC (P)
DYNC1I2 Polyclonal Antibody detects DYNC1I2 protein at cytosol on mouse hind brain by immunohistochemical analysis. Sample: Paraffin-embedded mouse hind brain. DYNC1I2 Polyclonal Antibody (Product # PA5-22229) dilution: 1:500. Antigen Retrieval: EDTA based buffer, pH 8.0, 15 min.
产品信息
PA5-22229
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant protein fragment contain a sequence corresponding to a region within amino acids 129 and 366 (Q13409) of DYNC1I2
偶联物
形式
Liquid
浓度
0.3 mg/mL
纯化类型
Antigen affinity chromatography
保存液
0.1M tris glycine, pH 7, with 10% glycerol
内含物
0.01% thimerosal
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_11154571
产品详细信息
Recommended positive controls: HeLa.
Predicted reactivity: Mouse (97%), Rat (97%), Xenopus laevis (93%), Pig (98%), Chicken (94%), Rhesus Monkey (100%), Bovine (98%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
Dyneins are multi-subunit, high molecular weight ATPases that interact with microtubules to generate force by converting the chemical energy of ATP into the mechanical energy of movement. Cytoplasmic or axonemal Dynein heavy, intermediate, light and light-intermediate chains are all components of minus end-directed motors; the complex that transports cellular cargos towards the central region of the cell. Axonemal Dynein motors contain one to three non-identical heavy chains and cause a sliding of microtubules in the axonemes of cilia and flagella in a mechanism necessary for cilia to beat and propel the cell. Cytoplasmic Dynein is an approximately 12 subunit complex of two heavy chains, two intermediate chains to anchor Dynein to its cargo, four smaller intermediate chains and several light chains. It performs functions necessary for cell survival such as organelle transport and centrosome assembly. The carboxy-terminus of Dynein is important for microtubule-dependent motility and is highly conserved, while the amino-terminal regions are more variable. Several proteins regulate Dynein activity, including Dynactin, LIS1 and nudel (nudE-like).
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Cytoplasmic dynein 1 intermediate chain 2; Cytoplasmic dynein intermediate chain 2; cytoplasmic dynein intermediate chain 2 isoform 2.1; cytoplasmic dynein intermediate chain 2 isoform 2.2; cytoplasmic dynein intermediate chain 2 isoform 2.5; DH IC-2; Dynein intermediate chain 2, cytosolic; dynein, cytoplasmic 1, intermediate chain 2; dynein, cytoplasmic, intermediate chain 2; dynein, cytoplasmic, intermediate polypeptide 2; testis tissue sperm-binding protein Li 66n
基因别名: 3110079H08Rik; AW554389; DIC74; DNCI2; DNCIC2; DYNC1I2; IC2
UniProt ID: (Human) Q13409, (Mouse) O88487
Entrez Gene ID: (Human) 1781, (Mouse) 13427
