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产品信息
1829-MSM1-P1ABX
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG1, kappa
分类
Monoclonal
类型
Antibody
克隆号
6D8
抗原
Recombinant human DSG2 protein
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A/G
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
靶标信息
Desmosomes are cell-cell junctions between epithelial, myocardial, and certain other cell types. Currently, three desmoglein subfamily members have been identified and all are members of the cadherin cell adhesion molecule superfamily. These desmoglein gene family members are located in a cluster on chromosome 18. This protein has been identified as the autoantigen of the autoimmune skin blistering disease pemphigus vulgaris.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: ARVC10; ARVD10; Cadherin family member 5; CMD1BB; Desmoglein-2; DSG-2; HDGC; MGC117034; MGC117036; MGC117037
基因别名: CDHF5; DSG2; HDGC
UniProt ID: (Human) Q14126
Entrez Gene ID: (Human) 1829
desmosome organization
Purkinje myocyte development
cell adhesion
homophilic cell adhesion via plasma membrane adhesion molecules
response to progesterone
maternal process involved in female pregnancy
bundle of His cell-Purkinje myocyte adhesion involved in cell communication
regulation of heart rate by cardiac conduction
regulation of ventricular cardiac muscle cell action potential
