Target of Interest
Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
产品信息
PA5-36051
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide corresponding to amino acids 18-72 of human E2F4
偶联物
Unconjugated
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 50% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2553346
产品详细信息
This antibody detects endogenous protein at a molecular weight of 44 kDa.
Purity is >95% by SDS-PAGE.
靶标信息
E2F was originally identified through its role in transcriptional activation of the adenovirus E2 promoter. Sequences homologous to the E2F binding site have been found upstream of a number of genes that encode proteins with putative functions in the G1 and S phases of the cell cycle. E2F-1 is a member of a broader family of transcriptional regulators including E2F-2, E2F-3, E2F-4, E2F-5 and E2F-6, each of which forms heterodimers with a second protein, DP-1, forming an "active" E2F transcriptional regulatory complex.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
篇参考文献 (0)
您是否在文献中引用过该产品？请点击下方按钮邮件告知我们。
生物信息学
蛋白别名: E2F transcription factor 4, p107/p130-binding; E2F transcription factor 5, p130-binding; E2F-4; E2F-5; p107/p130-binding protein; Transcription factor E2F4; Transcription factor E2F5
基因别名: 2010111M04Rik; AI427446; AU024671; E2F-4; E2F-5; E2F4; E2F5
UniProt ID: (Human) Q16254, (Human) Q15329, (Mouse) Q8R0K9, (Mouse) Q61502
Entrez Gene ID: (Human) 1874, (Human) 1875, (Rat) 100360427, (Mouse) 104394, (Mouse) 13559, (Rat) 116651
RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
DNA binding
transcription factor activity, sequence-specific DNA binding
protein binding
transcription factor binding
protein domain specific binding
promoter-specific chromatin binding
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
sequence-specific DNA binding
RNA metabolism protein
nucleic acid metabolism protein
general transcription factor
regulation of transcription involved in G1/S transition of mitotic cell cycle
epithelial cell development
transcription from RNA polymerase II promoter
cell volume homeostasis
DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
blood circulation
organ morphogenesis
regulation of cell proliferation
motile cilium assembly
positive regulation of transcription from RNA polymerase II promoter
centriole assembly
multi-ciliated epithelial cell differentiation
transcription, DNA-templated
cell projection organization
regulation of cell cycle
regulation of cell size
cilium assembly
mitotic cell cycle
regulation of transcription, DNA-templated
cell cycle
G1/S transition of mitotic cell cycle
