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产品信息
PA5-37453
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide corresponding to amino acids 1245-1296 of human EGFL4
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 50% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2554070
产品详细信息
This antibody detects endogenous protein at a molecular weight of 255 kDa.
Purity is >95% by SDS-PAGE.
靶标信息
EGFL4 (epidermal growth factor-like protein 4), also known as MEGF8 (multiple epidermal growth factor-like domains protein 8) or C19orf49, is a 2,845 amino acid single-pass type I membrane protein. EGFL4 contains 2 CUB domains, 5 EGF-like domains, 12 Kelch repeats, 4 laminin EGF-like domains and 7 PSI domains. Existing as two alternatively spliced isoforms, the gene encoding EGFL4 maps to human chromosome 19q13.2. Chromosome 19 consists of approximately 63 million bases, makes up over 2% of human genomic DNA, and is recognized for having the greatest gene density of the human chromosomes. It is the genetic home for a number of immunoglobulin superfamily members including the killer cell and leukocyte Ig-like receptors.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: EGF-like domain-containing protein 4; EGF-like protein 4; EGF-like-domain, multiple 4; Epidermal growth factor-like protein 4; HBV pre-s2 binding protein 1; HBV pre-S2-binding protein 1; hepatitis B virus pre-S2-binding protein 1; multiple EGF-like domain protein 4; Multiple EGF-like domains protein 8; multiple EGF-like-domains 8; Multiple epidermal growth factor-like domains protein 8
基因别名: AW049492; b2b1702Clo; b2b288Clo; C19orf49; CRPT2; EGFL4; KIAA0817; m687Ddg; MEGF8; mKIAA0817; SBP1
UniProt ID: (Human) Q7Z7M0, (Mouse) P60882
Entrez Gene ID: (Human) 1954, (Rat) 114029, (Mouse) 269878
embryonic heart tube morphogenesis
regulation of gene expression
embryonic limb morphogenesis
BMP signaling pathway
limb morphogenesis
cell migration involved in gastrulation
embryonic skeletal system morphogenesis
positive regulation of axon extension involved in axon guidance
epiboly involved in gastrulation with mouth forming second
embryonic heart tube left/right pattern formation
left/right pattern formation
coronary vasculature development
determination of heart left/right asymmetry
determination of digestive tract left/right asymmetry
craniofacial suture morphogenesis
fasciculation of sensory neuron axon
epithelial cilium movement involved in determination of left/right asymmetry
nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry
