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Invitrogen

EGR1 Monoclonal Antibody (T.160.5)

高级验证

3个已发表图片

10 篇参考文献

查看其他23个EGR1抗体

说明书

实验方案

技术支持

货号 MA5-15008

CNY 5,153.00

100 µL

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说明书

实验方案

技术支持

Application

EGR1 Antibody in Immunocytochemistry (ICC/IF)

图: 1 / 7

EGR1 Antibody (MA5-15008) in ICC/IF

Immunofluorescent analysis of EGR1 in dissociated PC12 cells using an EGR1 monoclonal antibody (Product # MA5-15008) (green) and a MEK1/2 monoclonal antibody (red).

EGR1 Antibody in Western Blot, Immunohistochemistry (WB, IHC)

EGR1 Antibody in Western Blot, Immunohistochemistry (PFA fixed) (WB, IHC (PFA))

Product Image Gallery

EGR1 Antibody — Altered expression of proteins upon cell treatment demonstrates antibody specificity. Western blot using EGR1 Monoclonal Antibody (Product # MA5-15008), shows increased expression of proteins in PC-12 cells treated with NGF. {TM}

产品信息

MA5-15008

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:1,000

查看7篇已发表文章 7篇已发表文章

免疫组化 (IHC)

查看1篇已发表文章 1篇已发表文章

免疫组织化学（多聚甲醛固定） (IHC (PFA))

查看1篇已发表文章 1篇已发表文章

免疫细胞化学 (ICC/IF)

1:1,600

查看1篇已发表文章 1篇已发表文章

免疫沉淀 (IP)

1:50

染色质免疫沉淀实验 (ChIP)

1:50

产品规格

种属反应

Human, Mouse, Rat

已发表种属

Human, Mouse, Rat

宿主/亚型

Rabbit / IgG

分类

Monoclonal

类型

Antibody

克隆号

T.160.5

抗原

Synthetic peptide corresponding to the amino terminus of the sequence of human EGR1

查看免疫原

偶联物

Unconjugated

形式

Liquid

浓度

42 µg/mL

纯化类型

Affinity chromatography

保存液

0.01M HEPES, pH 7.5, with 100µg/mL BSA, 50% glycerol, 0.15M NaCl

内含物

<0.02% sodium azide

保存条件

-20°C

运输条件

Ambient (domestic); Wet ice (international)

RRID

AB_10977090

产品详细信息

It is not recommended to aliquot this antibody.

靶标信息

The protein encoded by this gene belongs to the EGR family of C2H2-type zinc-finger proteins. It is a nuclear protein and functions as a transcriptional regulator. The products of target genes it activates are required for differentitation and mitogenesis. Studies suggest this is a cancer suppresor gene.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

Product References

Liproxstatin-1 Alleviated Ischemia/Reperfusion-Induced Acute Kidney Injury via Inhibiting Ferroptosis.

Antioxidants (Basel, Switzerland)

Shi Z,Du Y,Zheng J,Tang W,Liang Q,Zheng Z,Liu B,Sun H,Wang K,Shao C

Published figure using EGR1 monoclonal antibody (Product # MA5-15008) in Western Blot

Wed Jan 31 00:00:00 UTC 2024

Differential Gain-of-Function Activity of Three p53 Hotspot Mutants In Vivo.

Cancer research

Xiong S,Chachad D,Zhang Y,Gencel-Augusto J,Sirito M,Pant V,Yang P,Sun C,Chau G,Qi Y,Su X,Whitley EM,El-Naggar AK,Lozano G

MA5-15008 was used in Western Blotting to show that p53 hotspot mutants inhibit wild-type p53 similarly but differ in their GOF activities, with stronger tumor-promoting activity in contact mutants and distinct protein partners of each mutant driving tumorigenesis and metastasis.

Mon May 16 00:00:00 UTC 2022

m6A Regulator-Mediated RNA Methylation Modification Patterns Regulate the Immune Microenvironment in Osteoarthritis.

Frontiers in genetics

Duan Y,Yu C,Yan M,Ouyang Y,Ni S

MA5-15008 was used in Western Blot to investigate the role of RNA n6 methyl adenosine (m6A) modification in the immune microenvironment of osteoarthritis (OA), revealing distinct m6A regulatory patterns in healthy and OA samples, with upregulated YTHDF3 expression positively correlated with specific immune cells and pathways related to endoplasmic reticulum oxidative stress and mitochondrial autophagy.

Sat Jul 16 00:00:00 UTC 2022

Fasting-mimicking diet and hormone therapy induce breast cancer regression.

Nature

Caffa I,Spagnolo V,Vernieri C,Valdemarin F,Becherini P,Wei M,Brandhorst S,Zucal C,Driehuis E,Ferrando L,Piacente F,Tagliafico A,Cilli M,Mastracci L,Vellone VG,Piazza S,Cremonini AL,Gradaschi R,Mantero C,Passalacqua M,Ballestrero A,Zoppoli G,Cea M,Arrighi A,Odetti P,Monacelli F,Salvadori G,Cortellino S,Clevers H,De Braud F,Sukkar SG,Provenzani A,Longo VD,Nencioni A

MA5-15008 was used in Western Blotting to support further clinical studies of a fasting-mimicking diet as an adjuvant to oestrogen therapy in hormone-receptor-positive breast cancer.

Wed Jul 01 00:00:00 UTC 2020

Identification and Validation of Potential Biomarkers and Their Functions in Acute Kidney Injury.

Frontiers in genetics

Chen J,Chen Y,Olivero A,Chen X

Published figure using EGR1 monoclonal antibody (Product # MA5-15008) in Immunohistochemistry (PFA fixed)

Mon Sep 28 00:00:00 UTC 2020

Identification and Validation of Potential Biomarkers and Their Functions in Acute Kidney Injury.

Frontiers in genetics

Chen J,Chen Y,Olivero A,Chen X

Published figure using EGR1 monoclonal antibody (Product # MA5-15008) in Immunohistochemistry (PFA fixed)

Mon Sep 28 00:00:00 UTC 2020

Identification and Validation of Potential Biomarkers and Their Functions in Acute Kidney Injury.

Frontiers in genetics

Chen J,Chen Y,Olivero A,Chen X

Published figure using EGR1 monoclonal antibody (Product # MA5-15008) in Immunohistochemistry (PFA fixed)

Mon Sep 28 00:00:00 UTC 2020

Identification and Validation of Potential Biomarkers and Their Functions in Acute Kidney Injury.

Frontiers in genetics

Chen J,Chen Y,Olivero A,Chen X

Published figure using EGR1 monoclonal antibody (Product # MA5-15008) in Immunohistochemistry (PFA fixed)

Mon Sep 28 00:00:00 UTC 2020

METTL3-mediated N⁶-methyladenosine mRNA modification enhances long-term memory consolidation.

Cell research

Zhang Z,Wang M,Xie D,Huang Z,Zhang L,Yang Y,Ma D,Li W,Zhou Q,Yang YG,Wang XJ

Published figure using EGR1 monoclonal antibody (Product # MA5-15008) in Immunofluorescence

Thu Nov 01 00:00:00 UTC 2018

METTL3-mediated N⁶-methyladenosine mRNA modification enhances long-term memory consolidation.

Cell research

Zhang Z,Wang M,Xie D,Huang Z,Zhang L,Yang Y,Ma D,Li W,Zhou Q,Yang YG,Wang XJ

Published figure using EGR1 monoclonal antibody (Product # MA5-15008) in Immunofluorescence

Thu Nov 01 00:00:00 UTC 2018

Melatonin attenuates scopolamine-induced memory/synaptic disorder by rescuing EPACs/miR-124/Egr1 pathway.

Molecular neurobiology

Wang X,Wang ZH,Wu YY,Tang H,Tan L,Wang X,Gao XY,Xiong YS,Liu D,Wang JZ,Zhu LQ

MA5-15008 was used in western blot to study the molecular mechanisms by which melatonin treatment improves memory in a scopolamine-induced amnesia model

Fri Feb 01 00:00:00 UTC 2013

生物信息学

蛋白别名: AT225; Early growth response protein 1; EGR-1; Krox-24 nuclear protein; Nerve growth factor-induced protein A; NGFI-A; Transcription factor ETR103; Transcription factor Zif268; Zinc finger protein 225; Zinc finger protein Krox-24

基因别名: A530045N19Rik; AT225; egr; Egr-1; EGR1; ETR103; G0S30; Krox-1; KROX-24; KROX24; Ngf1; NGF1-A; Ngfi; NGFI-A; NGFIA; TIS8; Zenk; Zfp-6; ZIF-268; Zif268; ZNF225

UniProt ID: (Human) P18146, (Rat) P08154, (Mouse) P08046

Entrez Gene ID: (Human) 1958, (Rat) 24330, (Mouse) 13653

功能

transcription regulatory region sequence-specific DNA binding RNA polymerase II regulatory region sequence-specific DNA binding transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding DNA binding transcription factor activity, sequence-specific DNA binding protein binding histone acetyltransferase binding sequence-specific DNA binding metal ion binding RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding double-stranded DNA binding transcription factor binding transcription regulatory region DNA binding nucleic acid binding C2H2 zinc finger transcription factor

参与通路

EGR1 Monoclonal Antibody (T.160.5)

EGR1 Antibody (MA5-15008) in ICC/IF

产品信息

MA5-15008

免疫印迹 (WB)

免疫组化 (IHC)

免疫组织化学（多聚甲醛固定） (IHC (PFA))

免疫细胞化学 (ICC/IF)

免疫沉淀 (IP)

染色质免疫沉淀实验 (ChIP)

种属反应

已发表种属

宿主/亚型

分类

类型

克隆号

抗原

偶联物

形式

浓度

纯化类型

保存液

内含物

保存条件

运输条件

RRID

产品详细信息

靶标信息

生物信息学

性能保障

随时为您服务

Your items have has been added!

EGR1 Monoclonal Antibody (T.160.5)

EGR1 Antibody (MA5-15008) in ICC/IF

产品信息

MA5-15008

免疫印迹 (WB)

免疫组化 (IHC)

免疫组织化学（多聚甲醛固定） (IHC (PFA))

免疫细胞化学 (ICC/IF)

免疫沉淀 (IP)

染色质免疫沉淀 实验 (ChIP)

种属反应

已发表种属

宿主/亚型

分类

类型

克隆号

抗原

偶联物

形式

浓度

纯化类型

保存液

内含物

保存条件

运输条件

RRID .st0{fill-rule:evenodd;clip-rule:evenodd;fill:#A2A2A2;}

产品详细信息

靶标信息

生物信息学

性能保障

随时为您服务

Your items have has been added!

染色质免疫沉淀实验 (ChIP)

RRID