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产品信息
PA5-61012
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
Unconjugated
形式
Liquid
浓度
0.1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2640949
产品详细信息
Immunogen sequence: AREAAFDAEY QRNPHRVDLD ILTFTIALTA SEVINPLIEE LGCDKFINRE
Highest antigen sequence identity to the following orthologs: Mouse - 90%, Rat - 90%.
靶标信息
EID2 interacts with EP300 and acts as a repressor of MYOD-dependent transcription and muscle differentiation. Inhibits EP300 histone acetyltransferase activity. Acts as a repressor of TGFB/SMAD transcriptional responses. It may act as a repressor of the TGFB/SMAD3-dependent signaling by selectively blocking formation of TGFB-induced SMAD3-SMAD4 complex.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: CREBBP/EP300 inhibitor 2; CREBBP/EP300 inhibitory protein 2; E1A like inhibitor of differentiation 2; EID-1-like inhibitor of differentiation 2; EID-2; EID2; EP300-interacting inhibitor of differentiation 2
基因别名: CRI2; EID-2; EID2
UniProt ID: (Human) Q8N6I1
Entrez Gene ID: (Human) 163126
negative regulation of transcription from RNA polymerase II promoter
transcription, DNA-templated
transforming growth factor beta receptor complex assembly
SMAD protein complex assembly
muscle organ development
regulation of transforming growth factor beta receptor signaling pathway
cell differentiation
negative regulation of transforming growth factor beta receptor signaling pathway
regulation of cell proliferation
negative regulation of transcription, DNA-templated
