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产品信息
H00001990-M02
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG2a, kappa
分类
Monoclonal
类型
Antibody
克隆号
4H5
抗原
ELA1 (NP_001962.3, 159 a.a. approximately 257 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
偶联物
形式
Liquid
浓度
See Label
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Sequence of this protein is as follows: LAQTLQQAYL PSVDYAICSS SSYWGSTVKN TMVCAGGDGV RSGCQGDSGG PLHCLVNGKY SVHGVTSFVS SRGCNVSRKP TVFTQVSAYI SWINNVIAS
靶标信息
Elastases form a subfamily of serine proteases that hydrolyze many proteins in addition to elastin. Humans have six structurally similar proteins elastase 1, 2, 2A, 2B, 3A, and 3B. Unlike other elastases, pancreatic elastase 1 is not expressed in the pancreas. To date, elastase 1 (ELA1) expression has only been detected in skin keratinocytes. Clinical literature that describes human elastase 1 activity in the pancreas is actually referring to elastase 2A.Elastases form a subfamily of serine proteases that hydrolyze many proteins in addition to elastin. Humans have six elastase genes which encode the structurally similar proteins elastase 1, 2, 2A, 2B, 3A, and 3B. Unlike other elastases, pancreatic elastase 1 is not expressed in the pancreas. To date, elastase 1 expression has only been detected in skin keratinocytes. Clinical literature that describes human elastase 1 activity in the pancreas is actually referring to elastase 2A.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Chymotrypsin-like elastase family member 1; chymotrypsin-like elastase family, member 1; elastase 1, pancreatic; Elastase-1; Pancreatic elastase 1
基因别名: CELA1; ELA1
UniProt ID: (Human) Q6ISM6
Entrez Gene ID: (Human) 1990
negative regulation of transcription from RNA polymerase II promoter
proteolysis
inflammatory response
post-embryonic development
Wnt signaling pathway
exocrine pancreas development
multicellular organism growth
regulation of cell proliferation
regulation of cell differentiation
positive regulation of angiogenesis
positive regulation of transcription from RNA polymerase II promoter
tissue remodeling
elastin catabolic process
pancreas morphogenesis
