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产品信息
PA5-92039
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human ELOVL4 (NP_0735631)
偶联物
形式
Liquid
浓度
1.13 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.05% ProClin 300
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2806361
产品详细信息
Immunogen sequence: MGLLDSEPGS VLNVVSTALN DTVEFYRWTW SIADKRVENW PLMQSPWPTL SISTLYLLFV WLGPKWMKDR EPFQMRLVLI IYNFGMVLLN LFIFRELFMG; Positive Samples: U-87MG, HT-29, OVCAR3, A-431, HeLa; Cellular Location: Endoplasmic reticulum membrane, Multi-pass membrane protein
靶标信息
This gene encodes a membrane-bound protein which is a member of the ELO family, proteins which participate in the biosynthesis of fatty acids. Consistent with the expression of the encoded protein in photoreceptor cells of the retina, mutations and small deletions in this gene are associated with Stargardt-like macular dystrophy (STGD3) and autosomal dominant Stargardt-like macular dystrophy (ADMD), also referred to as autosomal dominant atrophic macular degeneration.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 3-keto acyl-CoA synthase ELOVL4; cancer/testis antigen 118; elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 4; Elongation of very long chain fatty acids protein 4; elongation of very long chain fatty acids-like 4; ELOVL FA elongase 4; ELOVL fatty acid elongase 4; FLJ17667; FLJ92876; Very long chain 3-ketoacyl-CoA synthase 4; Very long chain 3-oxoacyl-CoA synthase 4; Very long chain fatty acid elongase 4; very-long-chain 3-oxoacyl-CoA synthase 4
基因别名: ADMD; CT118; ELOVL4; ISQMR; SCA34; STGD2; STGD3
UniProt ID: (Human) Q9GZR5, (Mouse) Q9EQC4
Entrez Gene ID: (Human) 6785, (Rat) 315851, (Mouse) 83603
fatty acid biosynthetic process
unsaturated fatty acid biosynthetic process
detection of visible light
fatty acid elongation, saturated fatty acid
sphingolipid biosynthetic process
fatty acid elongation, monounsaturated fatty acid
fatty acid elongation, polyunsaturated fatty acid
long-chain fatty-acyl-CoA biosynthetic process
very long-chain fatty acid biosynthetic process
biological_process
lipid metabolic process
fatty acid metabolic process
