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产品信息
H00002021-B02P
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG
分类
Polyclonal
类型
Antibody
抗原
ENDOG (AAH04922.1, 50 a.a. approximately 297 a.a) full-length human protein.
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
产品详细信息
Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: ELPPVPGGPR GPGELAKYGL PGLAQLKSRE SYVLCYDPRT RGALWVVEQL RPERLRGDGD RRECDFREDD SVHAYHRATN ADYRGSGFDR GHLAAAANHR WSQKAMDDTF YLSNVAPQVP HLNQNAWNNL EKYSRSLTRS YQNVYVCTGP LFLPRTEADG KSYVKYQVIG KNHVAVPTHF FKVLILEAAG GQIELRTYVM PNAPVDEAIP LERFLVPIES IERASGLLFV PNILARAGSL KAITAGSK
靶标信息
The protein encoded by this gene is a nuclear encoded endonuclease that is localized in the mitochondrion. The encoded protein is widely distributed among animals and cleaves DNA at GC tracts. This protein is capable of generating the RNA primers required by DNA polymerase gamma to initiate replication of mitochondrial DNA.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Endo G; Endonuclease G, mitochondrial; mitochondrial endonuclease G
基因别名: ENDOG
UniProt ID: (Human) Q14249
Entrez Gene ID: (Human) 2021
in utero embryonic development
apoptotic DNA fragmentation
DNA recombination
aging
response to mechanical stimulus
response to estradiol
response to tumor necrosis factor
neuron death in response to oxidative stress
response to antibiotic
cellular response to calcium ion
cellular response to glucose stimulus
cellular response to hypoxia
positive regulation of hydrogen peroxide-mediated programmed cell death
positive regulation of apoptotic DNA fragmentation
