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产品信息
H00057634-M01
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG2a, kappa
分类
Monoclonal
类型
Antibody
克隆号
2A7
抗原
EP400 (NP_056224.2, 743 a.a. approximately 850 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
偶联物
形式
Liquid
浓度
0.46 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
产品详细信息
Product may be used with Western Blot (Transfected lysate).
Immunogen sequence: QVHQRIAELR KAGLWSQRRL PKLQEAPRPK SHWDYLLEEM QWMATDFAQE RRWKVAAAKK LVRTVVRHHE EKQLREERGK KEEQSRLRRI AASTAREIEC FWSNIEQV
靶标信息
Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. May be required for transcriptional activation of E2F1 and MYC target genes during cellular proliferation. The NuA4 complex ATPase and helicase activities seem to be, at least in part, contributed by the association of RUVBL1 and RUVBL2 with EP400. May regulate ZNF42 transcription activity.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: CAG repeat protein 32; Domino homolog; E1A-binding protein p400; hDomino; p400 kDa SWI2/SNF2-related protein; p400 SWI2/SNF2-related protein; trinucleotide repeat containing 12; Trinucleotide repeat-containing gene 12 protein
基因别名: CAGH32; EP400; KIAA1498; KIAA1818; P400; TNRC12
UniProt ID: (Human) Q96L91
Entrez Gene ID: (Human) 57634
