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EPHA3 Antibody (H00002042-M01) in WB
Western blot analysis of EPHA3 over-expressed 293 cell line, cotransfected with EPHA3 Validated Chimera RNAi (Cat # H00002042-R01V ) (Lane 2) or non-transfected control (Lane 1). Blot probed with EPHA3 monoclonal antibody (M01) clone 3A12 (Cat # H00002042-M01). GAPDH ( 36.1 kDa ) used as specificity and loading control.
产品信息
H00002042-M01
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG1, kappa
分类
Monoclonal
类型
Antibody
克隆号
3A12
抗原
EPHA3 (AAH63282, 202 a.a. approximately 326 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
偶联物
形式
Liquid
浓度
See Label
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Sequence of this protein is as follows: CPFTVKNLAM FPDTVPMDSQ SLVEVRGSCV NNSKEEDPPR MYCSTEGEWL VPIGKCSCNA GYEERGFMCQ ACRPGFYKAL DGNMKCAKCP PHSSTQEDGS MNCRCENNYF RADKDPPSMA CTRPP
靶标信息
EPHA3 belongs to the ephrin receptor subfamily of the protein tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediated developmental events, particularly in the nervous system. EPHA3 encodes a protein that binds ephrin-A ligands and receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. EPHA3 binds ephrin-A ligands.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: EK4; EPH-like kinase 4; Eph-like tyrosine kinase 1; Ephrin type-A receptor 3; H TYRO4; HEK; Human embryo kinase; human embryo kinase 1; testicular tissue protein Li 64; TYRO4 protein tyrosine kinase; Tyrosine-protein kinase receptor ETK1; Tyrosine-protein kinase TYRO4
基因别名: EK4; EPHA3; ETK; ETK1; HEK; HEK4; TYRO4
UniProt ID: (Human) P29320
Entrez Gene ID: (Human) 2042
cell adhesion
regulation of epithelial to mesenchymal transition
positive regulation of neuron projection development
cell migration
peptidyl-tyrosine phosphorylation
regulation of actin cytoskeleton organization
regulation of GTPase activity
ephrin receptor signaling pathway
regulation of focal adhesion assembly
regulation of microtubule cytoskeleton organization
cellular response to retinoic acid
fasciculation of sensory neuron axon
fasciculation of motor neuron axon
