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Invitrogen
ERG Polyclonal Antibody
高级验证
This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated.
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ERG Antibody (PA5-49681) in WB
Western blot was performed using Anti-ERG Polyclonal Antibody (Product # PA5-49681) and a ~42 kDa band corresponding to ERG was observed across all the tissue extracts tested except Mouse Spleen which is reported to be negative. Tissue extracts (30 µg lysate) of Mouse Lung (Lane 1), Mouse Liver (Lane 2), Mouse Brain (Lane 3), Mouse Kidney (Lane 4) and Mouse Spleen (Lane 5) were electrophoresed using NuPAGE™ 10% Bis-Tris Protein Gel (Product # NP0302BOX). Resolved proteins were then transferred onto a nitrocellulose membrane (Product # IB23... View More
产品信息
PA5-49681
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Peptide sequence around aa.84~88(G-S-R-N-S) derived from Human ERG.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2635134
产品详细信息
The antibody detects endogenous level of total ERG protein.
靶标信息
v-ets erythroblastosis virus E26 oncogene like isoform 2 (ERG) is a transcriptional regulator. It may participate in transcriptional regulation through the recruitment of SETDB1 histone methyltransferase and subsequent modification of local chromatin structure.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: avian erythroblastosis virus E-26 (v-ets) oncogene related; ERG/EWS fusion gene; ERG/FUS fusion gene; ERG/TMPSSR2 fusion gene; ERG1; erythroblast transformation-specific transcription factor ERG variant 10; ets-related; H Kv11.3; HGNC:3446; KCNH2; Oncogene ERG; OTTHUMP00000115970; OTTHUMP00000208036; TMPRSS2/ERG fusion; Transcriptional regulator ERG; transcriptional regulator ERG (transforming protein ERG); Transforming protein ERG; v-ets avian erythroblastosis virus E26 oncogene homolog; v-ets avian erythroblastosis virus E26 oncogene related; v-ets erythroblastosis virus E26 oncogene homolog; v-ets erythroblastosis virus E26 oncogene like
基因别名: D030036I24Rik; ERG; Erg-3; p55
UniProt ID: (Human) P11308, (Mouse) Q920K9
Entrez Gene ID: (Human) 2078, (Rat) 170909, (Mouse) 13876
endocardial cushion development
endocardial cushion to mesenchymal transition involved in heart valve formation
transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
protein phosphorylation
signal transduction
multicellular organism development
cell proliferation
cell migration
cell differentiation
positive regulation of blood vessel remodeling
transcription from RNA polymerase II promoter
