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Invitrogen
ERG Polyclonal Antibody
高级验证
This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated.
图: 1 / 5
ERG Antibody (PA5-88524) in ICC/IF
Immunofluorescence analysis of Erg was performed using log phase Reh cells. The cells were fixed with 4% paraformaldehyde for 10 minutes, permeabilized with 0.1% Triton™ X-100 for 15 minutes, and blocked with 2% BSA for 45 minutes at room temperature. The cells were labeled with ERG Polyclonal Antibody (Product # PA5-88524) at 1:100 dilution in 0.1% BSA, incubated at 4 degree celsius overnight and then labeled with Donkey anti-Rabbit IgG (H+L) Highly Cross-Adsorbed Secondary Antibody, Alexa Fluor Plus 488 (Product # A32790) (1:2000 dilutio... View More
产品信息
PA5-88524
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 1-280 of human ERG (NP_8915481)
偶联物
形式
Liquid
浓度
0.54 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2804974
产品详细信息
Immunogen sequence: MASTIKEALS VVSEDQSLFE CAYGTPHLAK TEMTASSSSD YGQTSKMSPR VPQQDWLSQP PARVTIKMEC NPSQVNGSRN SPDECSVAKG GKMVGSPDTV GMNYGSYMEE KHMPPPNMTT NERRVIVPAD PTLWSTDHVR QWLEWAVKEY GLPDVNILLF QNIDGKELCK MTKDDFQRLT PSYNADILLS HLHYLRETPL PHLTSDDVDK ALQNSPRLMH ARNTGGAAFI FPNTSVYPEA TQRITTRPDL PYEPPRRSAW TGHGHPTPQS KAAQPSPSTV; Positive Samples: MCF7, THP-1, HeLa, BT-474, 293T; Cellular Location: Cytoplasm, Nucleus
靶标信息
v-ets erythroblastosis virus E26 oncogene like isoform 2 (ERG) is a transcriptional regulator. It may participate in transcriptional regulation through the recruitment of SETDB1 histone methyltransferase and subsequent modification of local chromatin structure.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: ERG/EWS fusion gene; ERG/FUS fusion gene; ERG/TMPSSR2 fusion gene; ERG1; erythroblast transformation-specific transcription factor ERG variant 10; ets-related; H Kv11.3; HGNC:3446; KCNH2; Oncogene ERG; OTTHUMP00000115970; OTTHUMP00000208036; TMPRSS2/ERG fusion; Transcriptional regulator ERG; transcriptional regulator ERG (transforming protein ERG); Transforming protein ERG; v-ets avian erythroblastosis virus E26 oncogene homolog; v-ets avian erythroblastosis virus E26 oncogene related; v-ets erythroblastosis virus E26 oncogene homolog; v-ets erythroblastosis virus E26 oncogene like
基因别名: ERG; erg-3; p55
UniProt ID: (Human) P11308
Entrez Gene ID: (Human) 2078
endocardial cushion development
endocardial cushion to mesenchymal transition involved in heart valve formation
transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
protein phosphorylation
signal transduction
multicellular organism development
cell proliferation
cell migration
cell differentiation
positive regulation of blood vessel remodeling
