Invitrogen

Endothelin 2 Polyclonal Antibody

Endothelin 2 Antibody in Western Blot (WB)

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Endothelin 2 Antibody (PA5-113958) in WB

Western Blot of Human HepG2 using a Endothelin 2 Polyclonal Antibody (Product # PA5-113958).

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产品信息

PA5-113958

应用

建议稀释比

已发表文章

免疫印迹 (WB)

0.2-1 µg/mL

产品规格

种属反应

Human

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Synthetic peptide directed towards the n terminal region of human EDN2 (aa 1-50).

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.5 mg/mL

纯化类型

Affinity chromatography

保存液

PBS with 2% sucrose

内含物

0.09% sodium azide

保存条件

-20° C, Avoid Freeze/Thaw Cycles

运输条件

Wet ice

RRID

AB_2884473

产品详细信息

Immunogen sequence: MVSVPTTWCS VALALLVALH EGKGQAAATL EQPASSSHAQ GTHLRLRRCS

For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Predicted homology: Human: 100%; Mouse: 100%; Rabbit: 93%; Rat: 93%

靶标信息

Endothelins are endothelium-derived vasoconstrictor peptides. Endothelin 2, also known as ET-2, is a protein that in humans is encoded by the EDN2 gene. The secreted peptide (~2kD, 21 amino acids) is produced as a result of endothelin-2 precursor (~20 kD) processing and functions as a ligand for endothelin receptors which upon peptide binding modulates a wide array of cell signaling events. Diseases associated with endothelins include aortic disease and patent ductus arteriosus.

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