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Endothelin Receptor B Antibody (AER-002-GP200UL) in WB
Western blot analysis of rat (lanes 1 and 3) and mouse (lanes 2 and 4) brain lysates: - 1,2.Guinea pig Anti-Endothelin Receptor B Antibody (#AER-002-GP), (1:500).3,4. Guinea pig Anti-Endothelin Receptor B Antibody , preincubated with Endothelin Receptor B Blocking Peptide (#BLP-ER002).
产品信息
AER-002-GP200UL
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Guinea pig
/ IgG
分类
Polyclonal
类型
Antibody
抗原
CEMLRKKSGMQIALND, corresponding to amino acid residues 298-314 of rat ET-B, 3rd intracellular loop
偶联物
形式
Lyophilized
浓度
0.85 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.4, with 1% BSA
内含物
0.05% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Reconstitution: 25 µL, 50 µL or 0.2 mL double distilled water (DDW), depending on the sample size. The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20C. The reconstituted solution can be stored at 4C for up to 1 week. For longer periods, small aliquots should be stored at -20C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
靶标信息
Non-specific receptor for endothelin 1, 2, and 3. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: AU022549; endothelin B receptor; Endothelin receptor non-selective type; endothelin receptor subtype B1; Endothelin receptor type B; endothelin-B receptor; ET-B; Et-b receptor; Et-b-r; ET-BR; ET-RB; Etb receptor; Etb-svr; piebald; RP11-318G21.1
基因别名: ABCDS; Ednra; EDNRB; ET-B; ET-BR; ETB; ETB1; ETBR; ETR-b; ETRB; HSCR; HSCR2; Sox10m1; WS4A
UniProt ID: (Human) P24530, (Rat) P21451, (Mouse) P48302
Entrez Gene ID: (Human) 1910, (Rat) 50672, (Mouse) 13618
negative regulation of transcription from RNA polymerase II promoter
neural crest cell migration
positive regulation of protein phosphorylation
regulation of pH
G-protein coupled receptor signaling pathway
phospholipase C-activating G-protein coupled receptor signaling pathway
positive regulation of cytosolic calcium ion concentration
peripheral nervous system development
posterior midgut development
aging
regulation of blood pressure
positive regulation of cell proliferation
negative regulation of neuron maturation
response to organic cyclic compound
vein smooth muscle contraction
sensory perception of pain
cGMP-mediated signaling
melanocyte differentiation
regulation of fever generation
negative regulation of cellular protein metabolic process
response to lipopolysaccharide
enteric smooth muscle cell differentiation
positive regulation of urine volume
positive regulation of renal sodium excretion
epithelial fluid transport
vasoconstriction
vasodilation
negative regulation of apoptotic process
pigmentation
developmental pigmentation
macrophage chemotaxis
response to pain
enteric nervous system development
regulation of epithelial cell proliferation
regulation of sensory perception of pain
positive regulation of penile erection
cellular response to lipopolysaccharide
endothelin receptor signaling pathway
cell surface receptor signaling pathway
negative regulation of adenylate cyclase activity
nervous system development
signal transduction
