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Eotaxin 2 Antibody (500-M31-500UG) in ELISA
Sandwich ELISA: Assuming 100 µL/well, a concentration of 2.0-4.0 µg/mL of Eotaxin 2 Monoclonal Antibody (Product # 500-M31-500UG) will detect at least 100 pg/mL of Recombinant Human Eotaxin-2 (CCL24) when used with PeproTech Eotaxin 2 Polyclonal Antibody, Biotin (Product # 500-P103GBT-1MG) as the detection antibody at a concentration of approximately 0.050-0.10 µg/mL.
产品信息
500-M31-500UG
产品规格
种属反应
Human
宿主/亚型
Mouse
分类
Monoclonal
类型
Antibody
抗原
E.coli-derived Recombinant Human Eotaxin-2 (CCL24)
偶联物
形式
Lyophilized
浓度
1 mg/mL
纯化类型
Protein A
保存液
PBS
内含物
no preservative
保存条件
-20°C
运输条件
Ambient
RRID
AB_2929122
产品详细信息
AA Sequence of recombinant protein: VVIPSPCCMF FVSKRIPENR VVSYQLSSRS TCLKGGVIFT TKKGQQFCGD PKQEWVQRYM KNLDAKQKKA SPRARAVA.
Preparation: Produced in BALB/c mice immunized with highly pure Recombinant Human Eotaxin-2 (CCL24). Anti-Human Eotaxin-2 (CCL24)-specific antibody was purified from ascites fluid by Protein A affinity chromatography.
靶标信息
Eotaxin 2 belongs to the subfamily of small cytokine CC genes. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity on resting T lymphocytes, a minimal activity on neutrophils, and is negative on monocytes and activated T lymphocytes. The protein is also a strong suppressor of colony formation by a multipotential hematopoietic progenitor cell line.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: C-C motif chemokine 24; chemokine (C-C motif) ligand 24; CK-beta-6; Eosinophil chemotactic protein 2; Eotaxin-2; Eotaxin2; MPIF-2; Myeloid progenitor inhibitory factor 2; small inducible cytokine subfamily A (Cys-Cys), member 24; Small-inducible cytokine A24
基因别名: CCL24; Ckb-6; MPIF-2; MPIF2; SCYA24
UniProt ID: (Human) O00175
Entrez Gene ID: (Human) 6369
positive regulation of endothelial cell proliferation
monocyte chemotaxis
chemotaxis
inflammatory response
immune response
cytoskeleton organization
signal transduction
G-protein coupled receptor signaling pathway
cell-cell signaling
regulation of cell shape
positive regulation of cell migration
neutrophil chemotaxis
positive regulation of actin filament polymerization
positive regulation of GTPase activity
positive regulation of angiogenesis
eosinophil chemotaxis
lymphocyte chemotaxis
positive regulation of inflammatory response
chemokine-mediated signaling pathway
positive regulation of ERK1 and ERK2 cascade
cellular response to interferon-gamma
cellular response to interleukin-1
cellular response to tumor necrosis factor
positive regulation of eosinophil migration
