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产品信息
PA5-102643
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human CCL24(Accession O00175), corresponding to amino acid residues M86-C119.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice
RRID
AB_2852040
产品详细信息
Antibody detects endogenous levels of total CCL24.
靶标信息
Eotaxin 2 belongs to the subfamily of small cytokine CC genes. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity on resting T lymphocytes, a minimal activity on neutrophils, and is negative on monocytes and activated T lymphocytes. The protein is also a strong suppressor of colony formation by a multipotential hematopoietic progenitor cell line.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: C-C motif chemokine 24; CC chemokine CCL24; chemokine (C-C motif) ligand 24; CK-beta-6; Eosinophil chemotactic protein 2; Eotaxin-2; eotaxin-2-like protein; Eotaxin2; MPIF-2; Myeloid progenitor inhibitory factor 2; small inducible cytokine A24; small inducible cytokine subfamily A (Cys-Cys), member 24; Small-inducible cytokine A24
基因别名: CCL24; CKb-6; MPIF-2; MPIF2; SCYA24
UniProt ID: (Human) O00175, (Mouse) Q9JKC0
Entrez Gene ID: (Human) 6369, (Rat) 288593, (Mouse) 56221
positive regulation of endothelial cell proliferation
monocyte chemotaxis
chemotaxis
inflammatory response
immune response
cytoskeleton organization
signal transduction
G-protein coupled receptor signaling pathway
cell-cell signaling
regulation of cell shape
positive regulation of cell migration
neutrophil chemotaxis
positive regulation of actin filament polymerization
positive regulation of GTPase activity
positive regulation of angiogenesis
eosinophil chemotaxis
lymphocyte chemotaxis
positive regulation of inflammatory response
chemokine-mediated signaling pathway
positive regulation of ERK1 and ERK2 cascade
cellular response to interferon-gamma
cellular response to interleukin-1
cellular response to tumor necrosis factor
positive regulation of eosinophil migration
biological_process
