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Invitrogen
Eotaxin 2 Polyclonal Antibody
高级验证
This Antibody was verified by Neutralization to ensure that the antibody binds to the antigen stated.
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Eotaxin 2 Antibody (PA5-47486) in IHC (P)
Immunohistochemical analysis of Eotaxin 2 in immersion fixed paraffin-embedded sections of human skin. Samples were incubated in Eotaxin 2 polyclonal antibody (Product # PA5-47486) using a dilution of 15 µg/mL overnight at 4 °C. Tissue was stained with the Anti-Goat HRP-DAB Cell & Tissue Staining Kit (brown) and counterstained with hematoxylin (blue).
产品信息
PA5-47486
产品规格
种属反应
Human
宿主/亚型
Goat
/ IgG
分类
Polyclonal
类型
Antibody
抗原
E. coli-derived recombinant human CCL24/Eotaxin-2/MPIF-2 Val27-Cys119
偶联物
形式
Lyophilized
浓度
0.2 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS with 5% trehalose
内含物
No Preservative
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2610546
产品详细信息
In direct ELISAs and Western blots, approximately 10% cross-reactivity with recombinant mouse CCL24/Eotaxin-2/MPIF-2 is observed and less than 5% cross-reactivity with recombinant human (rh) MPIF-1 is observed.
Reconstitute at 0.2 mg/mL in sterile PBS.
Endoxin level is <0.10 EU per 1 µg of the antibody by the LAL method.
靶标信息
Eotaxin 2 belongs to the subfamily of small cytokine CC genes. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity on resting T lymphocytes, a minimal activity on neutrophils, and is negative on monocytes and activated T lymphocytes. The protein is also a strong suppressor of colony formation by a multipotential hematopoietic progenitor cell line.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: C-C motif chemokine 24; chemokine (C-C motif) ligand 24; CK-beta-6; Eosinophil chemotactic protein 2; Eotaxin-2; Eotaxin2; MPIF-2; Myeloid progenitor inhibitory factor 2; small inducible cytokine subfamily A (Cys-Cys), member 24; Small-inducible cytokine A24
基因别名: CCL24; Ckb-6; MPIF-2; MPIF2; SCYA24
UniProt ID: (Human) O00175
Entrez Gene ID: (Human) 6369
positive regulation of endothelial cell proliferation
monocyte chemotaxis
chemotaxis
inflammatory response
immune response
cytoskeleton organization
signal transduction
G-protein coupled receptor signaling pathway
cell-cell signaling
regulation of cell shape
positive regulation of cell migration
neutrophil chemotaxis
positive regulation of actin filament polymerization
positive regulation of GTPase activity
positive regulation of angiogenesis
eosinophil chemotaxis
lymphocyte chemotaxis
positive regulation of inflammatory response
chemokine-mediated signaling pathway
positive regulation of ERK1 and ERK2 cascade
cellular response to interferon-gamma
cellular response to interleukin-1
cellular response to tumor necrosis factor
positive regulation of eosinophil migration
