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Eotaxin Antibody (500-P41GBT-25UG) in WB
Western Blot: To detect hEotaxin by Western Blot analysis Eotaxin Polyclonal Antibody, Biotin (Product # 500-P41GBT-1MG) can be used at a concentration of 0.1-0.2 µg/mL. Used in conjunction with compatible secondary reagents the detection limit for Recombinant hEotaxin is 1.5-3.0 ng/lane, under either reducing or non-reducing conditions.
产品信息
500-P41GBT-25UG
产品规格
种属反应
Human
宿主/亚型
Goat
分类
Polyclonal
类型
Antibody
抗原
E.coli-derived Recombinant Human Eotaxin (CCL11)
偶联物
形式
Lyophilized
浓度
0.1-1.0 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS
内含物
no preservative
保存条件
-20°C
运输条件
Ambient
RRID
AB_2930531
产品详细信息
AA Sequence of recombinant protein: GPASVPTTCC FNLANRKIPL QRLESYRRIT SGKCPQKAVI FKTKLAKDIC ADPKKKWVQD SMKYLDQKSP TPKP.
Preparation: Produced from sera of goats immunized with highly pure Recombinant Human Eotaxin (CCL11). Anti-Human Eotaxin (CCL11)-specific antibody was purified by affinity chromatography and then biotinylated.
Sandwich ELISA: To detect hEotaxin by sandwich ELISA (using 100 µL/well antibody solution) a concentration of 0.25-1.0 µg/mL of this antibody is required. This biotinylated polyclonal antibody, in conjunction with PeproTech Polyclonal Anti-Human Eotaxin (500-P41G) as a capture antibody, allows the detection of at least 0.2-0.4 ng/well of Recombinant hEotaxin.
Western Blot: To detect hEotaxin by Western Blot analysis this antibody can be used at a concentration of 0.1-0.2 µg/mL. Used in conjunction with compatible secondary reagents the detection limit for Recombinant hEotaxin is 1.5-3.0 ng/lane, under either reducing or non-reducing conditions.
500-P41GBT-1MG will be provided as 2 x 500 µg
靶标信息
This gene is one of several Cys-Cys (CC) cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for eosinophils, but not mononuclear cells or neutrophils. This eosinophil specific chemokine assumed to be involved in eosinophilic inflammatory diseases such as atopic dermatitis, allergic rhinitis, asthma and parasitic infections.
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生物信息学
蛋白别名: C-C motif chemokine 11; chemokine (C-C motif) ligand 11; Eosinophil chemotactic protein; Eotaxin; Eotaxin 1; eotaxin-1; Eotaxin1; MGC22554; small inducible cytokine subfamily A (Cys-Cys), member 11 (eotaxin); Small-inducible cytokine A11
基因别名: CCL11; SCYA11
UniProt ID: (Human) P51671
Entrez Gene ID: (Human) 6356
positive regulation of endothelial cell proliferation
chronic inflammatory response
monocyte chemotaxis
mast cell chemotaxis
protein phosphorylation
cellular calcium ion homeostasis
chemotaxis
inflammatory response
cytoskeleton organization
actin filament organization
cell adhesion
signal transduction
G-protein coupled receptor signaling pathway
regulation of cell shape
response to radiation
response to virus
positive regulation of cell migration
neutrophil chemotaxis
positive regulation of actin filament polymerization
response to interleukin-13
positive regulation of GTPase activity
positive regulation of angiogenesis
eosinophil chemotaxis
lymphocyte chemotaxis
positive regulation of inflammatory response
branching involved in mammary gland duct morphogenesis
mammary duct terminal end bud growth
chemokine-mediated signaling pathway
ERK1 and ERK2 cascade
positive regulation of ERK1 and ERK2 cascade
response to interleukin-4
cellular response to interferon-gamma
cellular response to interleukin-1
cellular response to tumor necrosis factor
