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Eotaxin Antibody (PA5-78930) in WB
Western blot analysis of Eotaxin in Lane 1: recombinant mouse Eotaxin protein, Lane 2: recombinant mouse Eotaxin protein, Lane 3: recombinant mouse Eotaxin protein, Lane 4: recombinant mouse Eotaxin protein 1.25 ng using 10, 5 and 2.5 ng, respectively per well. Sample was incubated with Eotaxin (Product # PA5-78930).
产品信息
PA5-78930
产品规格
种属反应
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthetic peptide corresponding to a sequence at the C-terminus of mouse Eotaxin (73-93aa CADPKKKWVQDATKHLDQKLQ).
偶联物
形式
Lyophilized
浓度
500 µg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS with 5mg BSA
内含物
0.05mg sodium azide, 0.05mg thimerosal
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2746046
产品详细信息
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
靶标信息
This gene is one of several Cys-Cys (CC) cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for eosinophils, but not mononuclear cells or neutrophils. This eosinophil specific chemokine assumed to be involved in eosinophilic inflammatory diseases such as atopic dermatitis, allergic rhinitis, asthma and parasitic infections.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: C-C motif chemokine 11; Eosinophil chemotactic protein; Eotaxin; Eotaxin 1; Eotaxin1; MGC22554; small chemokine (C-C motif) ligand 11; small inducible cytokine A11; small inducible cytokine subfamily A11; Small-inducible cytokine A11
基因别名: Ccl11; eotaxin; Scya11
UniProt ID: (Rat) P97545, (Mouse) P48298
Entrez Gene ID: (Rat) 29397, (Mouse) 20292
positive regulation of endothelial cell proliferation
chronic inflammatory response
mast cell chemotaxis
immune response
cytoskeleton organization
actin filament organization
regulation of cell shape
positive regulation of cell migration
positive regulation of actin filament polymerization
response to interleukin-13
positive regulation of angiogenesis
eosinophil chemotaxis
branching involved in mammary gland duct morphogenesis
mammary duct terminal end bud growth
ERK1 and ERK2 cascade
response to interleukin-4
chemotaxis
inflammatory response
positive regulation of GTPase activity
