Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
产品信息
PA5-81557
产品规格
种属反应
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthetic peptide corresponding to the center region of the Mouse EphB2/Eph Receptor B2
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A, Antigen affinity chromatography
保存液
PBS
内含物
no preservative
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2788759
产品详细信息
This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%).
This antibody has specificity for Mouse EphB2.
靶标信息
EPHB2 is a receptor tyrosine kinase that belongs to the ephrin receptor family. Members of the Eph family of kinases play important roles in diverse biological processes including nervous system development, angiogenesis and neural synapsis formation and maturation. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. EphB4 binds to ephrin-B2 and plays an essential role in vascular development.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
篇参考文献 (0)
您是否在文献中引用过该产品？请点击下方按钮邮件告知我们。
生物信息学
蛋白别名: EFL6; EFNB3; EPH B2; EPHB3; Ephrin B1; Ephrin B2; Ephrin B3; Ephrin B4; Ephrin type-B receptor 2; EphrinB1; EphrinB2; EphrinB3; EphrinB4; EPLG8; ETK2; HEK-6; HEK2; LERK8; MGC87492; Neural kinase; Nuk receptor tyrosine kinase; TYRO6; Tyrosine-protein kinase receptor EPH-3; Tyrosine-protein kinase receptor SEK-3
基因别名: Cek5; Drt; Ephb2; Epth3; Erk; ETECK; Hek5; Nuk; Prkm5; Qek5; Sek3; Tyro5
UniProt ID: (Mouse) Q6GTQ7
Entrez Gene ID: (Mouse) 13844
nucleotide binding
protein kinase activity
protein tyrosine kinase activity
transmembrane receptor protein tyrosine kinase activity
receptor activity
ephrin receptor activity
transmembrane-ephrin receptor activity
receptor binding
protein binding
ATP binding
axon guidance receptor activity
kinase activity
transferase activity
transferase activity, transferring phosphorus-containing groups
identical protein binding
transmembrane signal receptor
cell morphogenesis
angiogenesis
urogenital system development
protein phosphorylation
transmembrane receptor protein tyrosine kinase signaling pathway
multicellular organism development
nervous system development
axon guidance
axonal fasciculation
learning
organ morphogenesis
phosphorylation
peptidyl-tyrosine phosphorylation
optic nerve morphogenesis
central nervous system projection neuron axonogenesis
corpus callosum development
retinal ganglion cell axon guidance
inner ear morphogenesis
ephrin receptor signaling pathway
regulation of neuronal synaptic plasticity
positive regulation of long-term neuronal synaptic plasticity
camera-type eye morphogenesis
regulation of axonogenesis
negative regulation of axonogenesis
regulation of body fluid levels
positive regulation of synapse assembly
palate development
dendritic spine development
dendritic spine morphogenesis
commissural neuron axon guidance
