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MA5-15394 targets EphB3 in indirect ELISA, IHC and WB applications and shows reactivity with Human samples.
The MA5-15394 immunogen is purified recombinant fragment of EphB3 (aa39-212) expressed in E. Coli.
MA5-15394 has been successfully used in immunohistochemistry analysis of Ephb3 in mouse E16.5 frozen lung sections.
EPHB3 is a receptor tyrosine kinase that belongs to the ephrin receptor family. Members of the Eph family of kinases play important roles in diverse biological processes including nervous system development, angiogenesis and neural synapsis formation and maturation. The ephrin ligands and Eph receptors display reciprocal expression in vivo. Developing and adult neural tissue express nearly all of the Eph receptors and ephrin ligands. Ephs and ephrins play a significant role in angiogenesis.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Developmental kinase 5; EK2; Embryonic kinase 2; EPH-like kinase 2; EPH-like tyrosine kinase 2; Ephrin type-B receptor 3; human embryo kinase 2; mDK-5; Tyrosine-protein kinase receptor SEK-4; Tyrosine-protein kinase TYRO6
基因别名: AW456895; Cek10; EK2; EPHB3; ETK2; HEK2; MDK5; Sek4; TYRO6
UniProt ID: (Human) P54753, (Mouse) P54754
Entrez Gene ID: (Human) 2049, (Mouse) 13845
分子生物学功能:
transmembrane signal receptor