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FBP1 Antibody (PA5-41999) in ICC/IF
Immunofluorescence analysis of FBP1 was performed using 70% confluent log phase MCF7 cells. The cells were fixed with 4% paraformaldehyde for 10 minutes, permeabilized with 0.1% Triton™ X-100 for 15 minutes, and blocked with 2% BSA for 1 hour at room temperature. The cells were labeled with FBP1 Polyclonal Antibody (Product # PA5-41999) at 5 microgram/mL in 0.1% BSA, incubated at 4 degree Celsius overnight and then labeled with Goat anti-Rabbit IgG (Heavy Chain) Superclonal™ Secondary Antibody, Alexa Fluor® 488 conjugate (Product # A27034)... View More
产品信息
PA5-41999
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide directed towards the N-terminal of human FBP1 (aa 114-163).
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A
保存液
PBS with 2% sucrose
内含物
0.09% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2609584
产品详细信息
Peptide sequence: YVVCFDPLDG SSNIDCLVSV GTIFGIYRKK STDEPSEKDA LQPGRNLVAA
Sequence homology: Cow: 86%; Dog: 86%; Guinea Pig: 93%; Horse: 93%; Human: 100%; Mouse: 100%; Rabbit: 93%; Rat: 86%; Zebrafish: 80%
靶标信息
Fructose-1,6-bisphosphatase 1, a gluconeogenesis regulatory enzyme, catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate and inorganic phosphate. Fructose-1,6-diphosphatase deficiency is associated with hypoglycemia and metabolic acidosis.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: D-fructose-1,6-bisphosphate 1-phosphohydrolase 1; EC 3.1.3.11; FBP 1; FBPase 1; fructose-1; Fructose-1,6-bisphosphatase 1; growth-inhibiting protein 17; Liver FBPase
基因别名: FBP; FBP1
UniProt ID: (Human) P09467
Entrez Gene ID: (Human) 2203
fructose metabolic process
fructose catabolic process
fructose 6-phosphate metabolic process
gluconeogenesis
regulation of gluconeogenesis
dephosphorylation
negative regulation of cell growth
cellular response to drug
negative regulation of glycolytic process
negative regulation of Ras protein signal transduction
protein homotetramerization
cellular response to magnesium ion
