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产品信息
MA5-31732
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG2b
分类
Monoclonal
类型
Antibody
克隆号
6F6G11
抗原
Purified recombinant fragment of human FBXL10 (AA: 457-555) expressed in E. coli.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein G
保存液
PBS
内含物
0.05% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2787356
产品详细信息
MA5-31732 has been tested in indirect ELISA.
靶标信息
This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs, which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class. Multiple alternatively spliced transcript variants have been found for this gene, but the full-length nature of some variants has not been determined.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: [Histone-H3]-lysine-36 demethylase 1B; CXXC-type zinc finger protein 2; F-box and leucine-rich repeat protein 10; F-box protein FBL10; F-box/LRR-repeat protein 10; JEMMA (Jumonji domain, EMSY-interactor, methyltransferase motif) protein; JmjC domain-containing histone demethylation protein 1B; jumonji C domain-containing histone demethylase 1B; Jumonji domain-containing EMSY-interactor methyltransferase motif protein; lysine (K)-specific demethylase 2B; Lysine-specific demethylase 2B; Protein JEMMA; Protein-containing CXXC domain 2
基因别名: CXXC2; FBL10; FBXL10; JHDM1B; KDM2B; NDY1; PCCX2
UniProt ID: (Human) Q8NHM5
Entrez Gene ID: (Human) 84678
negative regulation of transcription from RNA polymerase II promoter
transcription, DNA-templated
spermatogenesis
midbrain-hindbrain boundary morphogenesis
fourth ventricle development
lateral ventricle development
third ventricle development
initiation of neural tube closure
positive regulation of cell growth
forebrain development
midbrain development
hindbrain development
histone H2A monoubiquitination
negative regulation of neuron apoptotic process
embryonic camera-type eye morphogenesis
oxidation-reduction process
histone H3-K36 demethylation
positive regulation of stem cell population maintenance
negative regulation of neural precursor cell proliferation
