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产品信息
PA5-97111
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 27-290 of human FcRn (NP_0040981)
偶联物
形式
Liquid
浓度
2.77 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.09% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2808913
产品详细信息
Immunogen sequence: HLSLLYHLTA VSSPAPGTPA FWVSGWLGPQ QYLSYNSLRG EAEPCGAWVW ENQVSWYWEK ETTDLRIKEK LFLEAFKALG GKGPYTLQGL LGCELGPDNT SVPTAKFALN GEEFMNFDLK QGTWGGDWPE ALAISQRWQQ QDKAANKELT FLLFSCPHRL REHLERGRGN LEWKEPPSMR LKARPSSPGF SVLTCSAFSF YPPELQLRFL RNGLAAGTGQ GDFGPNSDGS FHASSSLTVK SGDEHHYCCI VQHAGLAQPL RVEL
Positive Samples: HL-60, Mouse brain, Mouse small intestine, Mouse liver, Mouse kidney; Cellular Location: Cell membrane, Single-pass type I membrane protein
靶标信息
FCGRT binds to the Fc region of monomeric immunoglobulins gamma. It mediates the uptake of IgG from milk. It plays a possible role in transfer of immunoglobulin G from mother to fetus.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Fc fragment immunoglobulin G receptor; Fc fragment of IgG, receptor, transporter, alpha; Fc receptor, IgG, alpha chain transporter; FcRn; FcRn alpha chain; heavy chain of the major histocompatibility complex class I-like Fc receptor; IgG Fc fragment receptor transporter alpha chain; IgG receptor FcRn large subunit p51; immunoglobulin receptor, intestinal, heavy chain; major histocompatibility complex class I-like Fc receptor; Neonatal Fc receptor; neonatal Fc-receptor for Ig; transmembrane alpha chain of the neonatal receptor
基因别名: alpha-chain; FCGRT; FCRN
UniProt ID: (Human) P55899, (Rat) P13599, (Mouse) Q61559
Entrez Gene ID: (Human) 2217, (Rat) 29558, (Mouse) 14132
