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Immunogen sequence: KAAVKSKKAT DTYKLYVEKY ALAKADFEQK MTETAQKFQD IEETHLIHIK EIIGSLSNAI KEIHLQIG
Highest antigen sequence identity to the following orthologs: Mouse - 97%, Rat - 99%.
FCHO2 (FCH domain only 2) is a ubiquitously expressed member of the FCFBS superfamily characterized by FES-CIP4 homology (FCH) domain, an FBH domain, and an SH3 domain. Both FCHO2 and the related protein FCHO1 are mediators of clathrin-mediated endocytosis, acting to sculpt the initial bud site and recruit the clathrin machinery for clathrin-coated vesicle formation. FCHO2 binds to Eps15, an important adaptor protein in clathrin-mediated endocytosis.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: F-BAR domain only protein 2; FCH domain only protein 2
基因别名: FCHO2
UniProt ID: (Human) Q0JRZ9
Entrez Gene ID: (Human) 115548