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7TM Antibodies
FFA2 Polyclonal Antibody
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FIGURE: 1 / 4
FFA2 Antibody (7TM0226N) in WB
Validation of the FFA2 in transfected HEK293 cells. Flp-In TREx HEK293 cells were induced to express human FFA2 DREADD-eYFP were treated with vehicle or 100 nM sorbate for 5 min. FFA2 receptors were enriched using a GFP trap and immunoblotted with the phosphorylation-independent anti-FFA2 antibody (7TM0226N-IC) at a dilution of 1:1,000.
Product Details
7TM0226N
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthetic peptide presents the carboxyl - terminal tail of human FFA2.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
Dulbecco's PBS, pH 7.4
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
G protein-coupled receptors (GPCRs, or GPRs) contain 7 transmembrane domains and transduce extracellular signals through heterotrimeric G proteins. GPCR GPR43 is a member of this family (subfamily carboxylic acid). It expression has been reported primarily in immune cells including monocytes and neutrophils. An EST has been isolated from a human pancreatic library.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: fatty acid receptor 2; free fatty acid activated receptor 2; Free fatty acid receptor 2; G protein-coupled receptor 43; G-protein coupled receptor 43
Gene Aliases: FFA2; FFA2R; FFAR2; GPCR43; GPR43
UniProt ID: (Human) O15552
Entrez Gene ID: (Human) 2867
leukocyte chemotaxis involved in inflammatory response
mucosal immune response
regulation of acute inflammatory response
positive regulation of cytokine production involved in immune response
cell surface pattern recognition receptor signaling pathway
positive regulation of acute inflammatory response to non-antigenic stimulus
G-protein coupled receptor signaling pathway
lipid storage
positive regulation of chemokine production
glucose homeostasis
fat cell differentiation
cellular response to fatty acid
regulation of peptide hormone secretion
positive regulation of interleukin-8 secretion
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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