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FFA2, FFA2 Receptor Antibody (7TM0226N-IC) in IHC (P)
Immunohistochemical identification of FFA2 Receptor in pancreas. Sections were dewaxed, microwaved in citric acid, and incubated with anti-FFA2 (FFA2 Receptor) antibody (7TM0226N-IC) at a dilution of 1:100. Sections were then sequentially treated with biotinylated anti-rabbit IgG and avidin-biotin solution. Color was developed by incubation in 3-amino-9-ethylcarbazole (AEC) , and sections were counterstaine... View More
产品信息
7TM0226N-IC
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
已发表种属
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthetic peptide presents the carboxyl - terminal tail of human FFA2.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
Dulbecco's PBS, pH 7.4
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice (domestic); Dry ice (international)
靶标信息
G protein-coupled receptors (GPCRs, or GPRs) contain 7 transmembrane domains and transduce extracellular signals through heterotrimeric G proteins. GPCR GPR43 is a member of this family (subfamily carboxylic acid). It expression has been reported primarily in immune cells including monocytes and neutrophils. An EST has been isolated from a human pancreatic library.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: fatty acid receptor 2; free fatty acid activated receptor 2; Free fatty acid receptor 2; G protein-coupled receptor 43; G-protein coupled receptor 43; Leukocyte-specific STAT-induced GPCR
基因别名: FFA2; FFA2R; FFAR2; GPCR43; GPR43; Lssig
UniProt ID: (Human) O15552, (Rat) Q76EI6, (Mouse) Q8VCK6
Entrez Gene ID: (Human) 2867, (Rat) 292794, (Mouse) 233079
leukocyte chemotaxis involved in inflammatory response
mucosal immune response
regulation of acute inflammatory response
positive regulation of cytokine production involved in immune response
cell surface pattern recognition receptor signaling pathway
positive regulation of acute inflammatory response to non-antigenic stimulus
G-protein coupled receptor signaling pathway
lipid storage
positive regulation of chemokine production
glucose homeostasis
fat cell differentiation
cellular response to fatty acid
regulation of peptide hormone secretion
positive regulation of interleukin-8 secretion
biological_process
immune system process
inflammatory response
signal transduction
