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NeoBiotechnologies
Antibody is stable for 24 months.
Positive Control: Human kidney or breast cancer. Cellular Localization: Secreted (extracellular)
Specificity Comments: Fibroblast growth factor-1 (FGF-1), also designated acidic FGF, and fibroblast growth factor-2 (FGF-2), also designated basic FGF, are members of a family of growth factors that stimulate proliferation of cells of mesenchymal, epithelial and neuroectodermal origin. Additional members of the FGF family include the oncogenes FGF-3 (Int2) and FGF-4 (hst/Kaposi), FGF-5, FGF-6, FGF-7 (KGF), FGF-8 (AIGF), FGF-9 (GAF) and FGF-10-FGF-23. Members of the FGF family share 30-55% amino acid sequence identity and similar gene structure and are capable of transforming cultured cells when overexpressed in transfected cells. Cellular receptors for FGFs are members of a second multigene family including four tyrosine kinases, designated Flg (FGFR-1), Bek (FGFR-L), TKF and FGFR-3.
The protein encoded by this gene is a member of the fibroblast growth factor family. FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. The function of this growth factor has not yet been determined.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: FGF; FGF-21; FGFL; Fibroblast growth factor; Fibroblast growth factor 21; PRO10196
基因别名: FGF21; UNQ3115/PRO10196
UniProt ID: (Human) Q9NSA1
Entrez Gene ID: (Human) 26291