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Antibody detects endogenous levels of total FGFR1/2.
FGFR1 is a member of the fibroblast growth factor receptor family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein consists of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. This particular family member binds both acidic and basic fibroblast growth factors and is involved in limb induction.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: bacteria-expressed kinase; Basic fibroblast growth factor receptor 1; BEK fibroblast growth factor receptor; bFGF-R; bFGF-R-1; BFGFR; c-fgr; CD331; CD332; FGF Receptor 2; FGF receptor-1; fgfr 1; FGFR-1; FGFR-2; FGFR1/PLAG1 fusion; Fibroblast growth factor receptor 1; Fibroblast growth factor receptor 2; FLT-2; FMS-like tyrosine kinase 2; fms-related tyrosine kinase 2; heparin-binding growth factor receptor; hydroxyaryl-protein kinase; K-sam; Keratinocyte growth factor receptor; KGFR; MFR; N-sam; protein tyrosine kinase, receptor like 14; Proto-oncogene c-Fgr; Soluble KGFR
基因别名: AU043015; AW208770; AW556123; BBDS; BEK; bFGF-R-1; BFGFR; BFR-1; c-fgr; CD331; CD332; CEK; CEK3; CFD1; Eask; ECCL; ECT1; FGFBR; FGFR-1; Fgfr-2; Fgfr-7; FGFR1; FGFR2; Fgfr7; FLG; FLT-2; FLT2; HBGFR; HH2; HRTFDS; Hspy; JWS; K-SAM; KAL2; KGFR; KGFRTr; KSAM; MFR; N-SAM; OGD; svs; TK14; TK25
UniProt ID: (Human) P11362, (Human) Q9UIH8, (Rat) Q04589, (Mouse) P16092, (Mouse) P21803
Entrez Gene ID: (Human) 2260, (Human) 2263, (Rat) 79114, (Mouse) 14182, (Mouse) 14183, (Rat) 25022