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Application
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FIGNL1 Antibody (PA5-117951) in IHC (P)
Immunohistochemical staining of human FIGNL1 in human kidney with FIGNL1 Polyclonal Antibody (Product # PA5-117951, 1:100 dilution, formalin-fixed paraffin embedded sections).
产品信息
PA5-117951
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
E. coli-derived Human FIGNL1 fragment
偶联物
Unconjugated
形式
Liquid
纯化类型
Antigen affinity chromatography, Protein A
保存液
PBS, pH 7
内含物
0.03% ProClin 300
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2902557
靶标信息
The mammalian Phospholipase Cg (PLCg) family has two closely related proteins, PLCg1 and PLCg2. The PLCg isozymes have the core structure domains and a unique array of domains containing an additional PH domain, two SH2 domains and one SH3 domain. In response to extracellular stimuli, such as hormones and growth factors, receptor tyrosine kinases (RTKs) phosphorylate and activate PLCg. Activated PLCg catalyzes hydrolysis of phosphatidylinositol 4,5-bisphosphate (PIP2) to produce the metabolic second messenger molecules inositol 1,4,5-triphosphate (IP3) and diacylglycerol (DAG).
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: fidgetin-like 1; Fidgetin-like protein 1
基因别名: FIGNL1
UniProt ID: (Human) Q6PIW4
Entrez Gene ID: (Human) 63979
osteoblast differentiation
regulation of double-strand break repair via homologous recombination
cytoplasmic microtubule organization
osteoblast proliferation
negative regulation of apoptotic process
ATP metabolic process
regulation of cell cycle
cellular response to ionizing radiation
negative regulation of intrinsic apoptotic signaling pathway
