Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
图: 1 / 1
FKBP1B Antibody (PA5-117152) in WB
Western blot analysis of FKBP1B in extracts of various cell lines. Samples were incubated with FKBP1B Polyclonal antibody (Product # PA5-117152) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 10s.
产品信息
PA5-117152
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthetic peptide corresponding to a sequence within amino acids 1-80 of human FKBP1B (NP_4733741)
偶联物
形式
Liquid
浓度
1.26 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.01% thimerosal
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2901782
产品详细信息
Positive Samples: Mouse brain, Rat brain
Immunogen sequence: MGVEIETISP GDGRTFPKKG QTCVVHYTGM LQNGKKFDSS RDRNKPFKFR IGKQEVIKGF EEGAAQLGPL SPLPICPHPC
靶标信息
Has the potential to contribute to the immunosuppressive and toxic effects of FK506 and rapamycin. PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
篇参考文献 (0)
您是否在文献中引用过该产品？请点击下方按钮邮件告知我们。
生物信息学
蛋白别名: 12.6 kDa FK506-binding protein; 12.6 kDa FKBP; 126 kDa FKBP; calstabin 2; Calstabin-2; FK506 binding protein 1B, 12.6 kDa; FK506-binding protein 12.6; FK506-binding protein 1B; FKBP-12.6; FKBP-126; FKBP-1B; FKBP126; h-FKBP-12; Immunophilin FKBP12.6; Peptidyl-prolyl cis-trans isomerase FKBP1B; PPIase FKBP1B; Rotamase
基因别名: 12.6kDa; AW494148; calstabin2; FKBP12.6; FKBP1B; FKBP1L; FKBP9; OTK4; PKBP1L; PPIase
UniProt ID: (Human) P68106, (Mouse) Q9Z2I2, (Rat) P97534
Entrez Gene ID: (Human) 2281, (Mouse) 14226, (Rat) 58950
protein peptidyl-prolyl isomerization
'de novo' protein folding
smooth muscle contraction
response to glucose
negative regulation of heart rate
regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion
release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
neuronal action potential propagation
protein maturation by protein folding
insulin secretion
negative regulation of protein phosphatase type 2B activity
response to vitamin E
ion transmembrane transport
calcium-mediated signaling using intracellular calcium source
protein refolding
T cell proliferation
response to hydrogen peroxide
positive regulation of axon regeneration
negative regulation of release of sequestered calcium ion into cytosol
positive regulation of sequestering of calcium ion
regulation of cytosolic calcium ion concentration
response to redox state
regulation of ryanodine-sensitive calcium-release channel activity
negative regulation of ryanodine-sensitive calcium-release channel activity
chaperone-mediated protein folding
negative regulation of insulin secretion involved in cellular response to glucose stimulus
cell communication by electrical coupling involved in cardiac conduction
regulation of cardiac conduction
regulation of heart rate
protein folding
positive regulation of cytosolic calcium ion concentration
release of sequestered calcium ion into cytosol
response to organic substance
