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FLRT3 (extracellular) Antibody (AFR-053-200UL) in IHC (F)
Expression of FLRT3 in mouse hippocampus. Immunohistochemical staining of perfusion-fixed frozen mouse brain sections with Anti-FLRT3 (extracellular) Antibody (#AFR-053), (1:200), followed by goat Anti-rabbit-AlexaFluor-488. A. Staining in the hippocampal dentate gyrus region, showed immunoreactivity (green) in the granule layer (G) and in the hilus (H, arrows). B. Pre-incubation of the Antibody with FLRT3 ... View More
产品信息
AFR-053-200UL
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
((C)KQPDIKNPKLTKDQR, corresponding to amino acid residues 387-401 of rat FLRT3, Extracellular, N-terminus
偶联物
Unconjugated
形式
Lyophilized
浓度
0.8 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.4, with 1% BSA
内含物
0.05% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Reconstitution: 25 µL, 50 µL or 0.2 mL double distilled water (DDW), depending on the sample size. The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20C. The reconstituted solution can be stored at 4C for up to 1 week. For longer periods, small aliquots should be stored at -20C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
靶标信息
This gene encodes a member of the fibronectin leucine rich transmembrane protein (FLRT) family. FLRTs may function in cell adhesion and/or receptor signaling. Their protein structures resemble small leucine-rich proteoglycans found in the extracellular matrix. This gene is expressed in many tissues. Two alternatively spliced transcript variants encoding the same protein have been described for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Fibronectin leucine rich transmembrane protein 3; Fibronectin-like domain-containing leucine-rich transmembrane protein 3; Leucine-rich repeat transmembrane protein FLRT3
基因别名: 5530600M07Rik; C430047I10Rik; FLRT3; HH21; KIAA1469; mKIAA1469; RGD1566005; UNQ856/PRO1865
UniProt ID: (Human) Q9NZU0, (Mouse) Q8BGT1, (Rat) B1H234
Entrez Gene ID: (Human) 23767, (Mouse) 71436, (Rat) 366205
axon guidance
negative chemotaxis
positive regulation of synapse assembly
cell adhesion
proepicardium cell migration involved in pericardium morphogenesis
negative regulation of protein kinase activity
synapse assembly
heart development
fibroblast growth factor receptor signaling pathway
cytokine-mediated signaling pathway
neuron projection development
negative regulation of JAK-STAT cascade
embryonic morphogenesis
response to axon injury
head development
cell-cell adhesion
neuron projection extension
