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产品信息
PA5-113676
产品规格
种属反应
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide directed towards the N-terminal region of Mouse Foxc2 (aa 51-100).
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Affinity chromatography
保存液
PBS with 2% sucrose
内含物
0.09% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2884191
产品详细信息
Immunogen sequence: GMGRSYAPYH HQPAAPKDLV KPPYSYIALI TMAIQNAPEK KITLNGIYQF
For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Predicted homology: Cow: 93%; Dog: 93%; Guinea Pig: 93%; Horse: 93%; Human: 93%; Mouse: 100%; Rat: 100%
靶标信息
Forkhead box protein C2 (FOXC2) is a transciptional activator and is characterized by a distinct DNA-binding forkhead domain. FOXC2 may be involved in the formation of special mesenchymal tissues. Mutations affecting the gene can cause lymphedema-distichiasis (LYD).
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: BF-3; Brain factor 3; Forkhead box protein C2; forkhead homolog 14; Forkhead-related protein FKHL14; Mesenchyme fork head protein 1; MFH-1 protein; Transcription factor FKH-14
基因别名: Fkh14; Fkhl14; Foxc2; Hfhbf3; MFH-1; Mfh1
UniProt ID: (Mouse) Q61850
Entrez Gene ID: (Mouse) 14234
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
DNA binding
transcription factor activity, sequence-specific DNA binding
transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
chromatin DNA binding
sequence-specific DNA binding
transcription regulatory region DNA binding
winged helix/forkhead transcription factor
negative regulation of transcription from RNA polymerase II promoter
skeletal system development
ossification
blood vessel development
patterning of blood vessels
metanephros development
ureteric bud development
somitogenesis
kidney development
lymph vessel development
lymphangiogenesis
blood vessel remodeling
heart morphogenesis
transcription, DNA-templated
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
transcription from RNA polymerase II promoter
Notch signaling pathway
multicellular organism development
heart development
cell proliferation
insulin receptor signaling pathway
response to hormone
positive regulation of endothelial cell migration
neural crest cell development
collagen fibril organization
positive regulation of integrin activation
positive regulation of cell adhesion mediated by integrin
embryonic heart tube development
positive regulation of vascular wound healing
camera-type eye development
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
regulation of organ growth
vascular endothelial growth factor receptor signaling pathway
paraxial mesoderm formation
paraxial mesodermal cell fate commitment
embryonic cranial skeleton morphogenesis
embryonic viscerocranium morphogenesis
embryonic skeletal system morphogenesis
artery morphogenesis
regulation of blood vessel size
ventricular cardiac muscle tissue morphogenesis
cardiac muscle cell proliferation
glomerular endothelium development
glomerular visceral epithelial cell differentiation
glomerular mesangial cell development
positive regulation of cell migration involved in sprouting angiogenesis
negative regulation of apoptotic process involved in outflow tract morphogenesis
