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FXYD1 Antibody (PA5-109744) in WB
Western blot analysis of FXYD1 in extracts of various cell lines. Samples were incubated with FXYD1 Polyclonal antibody (Product # PA5-109744) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit. Exposure time: 90s.
产品信息
PA5-109744
产品规格
种属反应
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthetic peptide corresponding to a sequence within amino acids 1-92 of human FXYD1 (NP_005022.2).
偶联物
Unconjugated
形式
Liquid
浓度
1.46 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.01% thimerosal
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2855155
产品详细信息
Immunogen sequence: MASLGHILVF CVGLLTMAKA ESPKEHDPFT YDYQSLQIGG LVIAGILFIL GILIVLSRRC RCKFNQQQRT GEPDEEEGTF RSSIRRLSTR RR
靶标信息
This gene encodes a member of the FXYD family of small membrane proteins that share a 35-amino acid signature sequence domain, beginning with the sequence PFXYD and containing 7 invariant and 6 highly conserved amino acids. The protein encoded by this gene is a plasma membrane substrate for several kinases, including protein kinase A, protein kinase C, NIMA kinase, and myotonic dystrophy kinase. It is thought to form an ion channel or regulate ion channel activity and act as an accessory protein of Na,K-ATPase. Alternatively spliced transcript variants have been described.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: FXYD domain-containing ion transport regulator 1; Phospholemman; Sodium Potassium ATPase; Sodium/potassium-transporting ATPase subunit FXYD1
基因别名: 0610012C17Rik; 1110006M24Rik; Fxyd1; Plm; Pml
UniProt ID: (Mouse) Q9Z239, (Rat) O08589
Entrez Gene ID: (Mouse) 56188, (Rat) 58971
transport
ion transport
chloride transport
positive regulation of organic acid transport
regulation of cytosolic calcium ion concentration
regulation of cardiac muscle cell contraction
regulation of cardiac muscle cell membrane potential
positive regulation of sodium ion export from cell
positive regulation of inorganic anion transmembrane transport
regulation of sodium ion transmembrane transporter activity
brain development
chloride transmembrane transport
