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产品信息
PA5-148279
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
E. coli-derived Human FXYD2 fragment
偶联物
形式
Liquid
浓度
100 µg/mL
纯化类型
Antigen affinity chromatography, Protein A
保存液
PBS, pH 7
内含物
0.03% ProClin 300
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
靶标信息
The human FXYD2 (pronounced fix-id) gene maps to chromosome 11q23 and encodes the gamma subunit of Na/K-ATPase (NKA). FXYD2 gamma subunit modulates NKA activity by inducing ion channel activity. The mammalian FXYD family maintains Na+ and K+ gradients between the intracellular and extracellular milieus of cells in processes such as renal Na+-reabsorption, muscle contraction and neuronal excitability. FXYDs are single-span membrane proteins that share a 35 amino acid signature domain, beginning with the sequence PFXYD and containing 7 invariant and 6 conserved amino acids. Other members of the FXYD family include FXYD1 (PLM, phospholemman), FXYD3 (Mat8, mammary tumor protein 8), FXYD4 (CHIF) and FXYD5 (RIC).
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生物信息学
蛋白别名: ATPase, Na+/K+ transporting, gamma 1 polypeptide; FXYD domain-containing ion transport regulator 2; Na(+)/K(+) ATPase subunit gamma; regulator 2; Sodium Potassium ATPase; Sodium pump gamma chain; Sodium/potassium-transporting ATPase subunit gamma
基因别名: ATP1C; ATP1G1; FXYD2; HOMG2
UniProt ID: (Human) P54710
Entrez Gene ID: (Human) 486
regulation of cell growth
transport
establishment or maintenance of transmembrane electrochemical gradient
ion transmembrane transport
sodium ion export from cell
regulation of cell proliferation
ATP hydrolysis coupled transmembrane transport
regulation of cardiac conduction
potassium ion import across plasma membrane
regulation of sodium ion transmembrane transporter activity
