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Invitrogen
Fetuin A Polyclonal Antibody
高级验证
This Antibody was verified by Knockdown to ensure that the antibody binds to the antigen stated.
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Fetuin A Antibody (PA5-47157) in WB
Western blot was performed using Anti- Fetuin A Polyclonal Antibody (Product # PA5-47157) and 50 kDa band corresponding to Fetuin A (AHSG) was observed in Hep G2 cells. whole cell extracts (30 µg lysate) of Hep G2 (Lane 1) and Hep G2 treated with Protein Transport Inhibitor (1X) for 4hrs (Lane 2), were electrophoresed using NuPAGE™ 4-12% Bis-Tris Protein Gel (Product # NP0322BOX). Resolved proteins were then transferred onto a nitrocellulose membrane (Product # IB23001) by iBlot® 2 Dry Blotting System (Product # IB21001). The blot was prob... View More
产品信息
PA5-47157
产品规格
种属反应
Human,
Mouse
已发表种属
Mouse
宿主/亚型
Goat
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Mouse myeloma cell line NS0-derived recombinant mouse Fetuin A/AHSG Ala19-Ile345
偶联物
形式
Lyophilized
浓度
0.2 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS with 5% trehalose
内含物
No Preservative
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2609021
产品详细信息
Approximately 5% cross-reactivity with recombinant human Fetuin A/AHSG is observed.
Reconstitute at 0.2 mg/mL in sterile PBS.
靶标信息
Alpha2-HS glycoprotein (AHSG), a glycoprotein present in the serum, is synthesized by hepatocytes. The AHSG molecule consists of two polypeptide chains, which are both cleaved from a proprotein encoded from a single mRNA. It is involved in several functions, such as endocytosis, brain development and the formation of bone tissue. The protein is commonly present in the cortical plate of the immature cerebral cortex and bone marrow hemopoietic matrix, and it has therefore been postulated that it participates in the development of the tissues. However, its exact significance is still obscure.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: Alpha-2-HS-glycoprotein; Alpha-2-Z-globulin; Ba-alpha-2-glycoprotein; Countertrypin; fetuin A; Fetuin-A; FetuinA
基因别名: A2HS; AHS; AHSG; FETUA; HSGA; PRO2743
UniProt ID: (Human) P02765, (Mouse) P29699
Entrez Gene ID: (Human) 197, (Mouse) 11625
skeletal system development
ossification
platelet degranulation
pinocytosis
acute-phase response
negative regulation of endopeptidase activity
regulation of bone mineralization
negative regulation of bone mineralization
negative regulation of phosphorylation
negative regulation of insulin receptor signaling pathway
regulation of inflammatory response
positive regulation of phagocytosis
negative regulation of biomineral tissue development
protein complex assembly
male gonad development
negative regulation of cell growth
positive regulation of bone resorption
negative regulation of protein tyrosine kinase activity
