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Fibrillarin Antibody (MA1-22000) in ICC/IF
Immunocytochemical analysis of rat neurons and glial stained with Fibrillarin Monoclonal Antibody (38F3) (Product # MA1-22000) (green) and with chicken antibody to neurofilament NF-H (red). Cells were counterstained with a fluorescent DNA probe (blue). Nuclear DNA is revealed with Hoechst dye (blue).
产品信息
MA1-22000
应用
建议稀释比
已发表文章
产品规格
种属反应
C. elegans,
Fruit fly,
Human,
Mouse,
Plant,
Rat,
Yeast
已发表种属
Human,
Plant
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
38F3
抗原
Yeast nuclear preparation (S cerevisiae)Hybridomas were screened by immunofluorescence on yeast cells and by western blotting on yeast protein homogenates (S cerevisiae)
偶联物
形式
Liquid
浓度
Conc. Not Determined
保存液
tissue culture supernatant
内含物
10mM sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2231906
产品详细信息
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
Nop1p / Fibrillarin was originally identified as a nucleolar protein of bakers yeast, Saccharomyces cerevisiae (accession P15646). The Nop1p protein is essential for yeast viability and is localized in the nucleoli. The human homologue of Nop1p is fibrillarin (accession P22087) a component of the nucleolar small nuclear ribonucleoprotein (snRNP) particle. The human fibrillarin gene is located on chromosome 19 (19q13. 1).
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: 34 kDa nucleolar scleroderma antigen; 34-kD nucleolar scleroderma antigen; AT20009p; CG5725-PA; CG5725-PB; CG5725-PC; CG5725-PD; CG5725-PE; CG5725-PF; CG5725-PG; fbl-PA; fbl-PB; fbl-PC; fbl-PD; fbl-PE; fbl-PF; fbl-PG; Histone-glutamine methyltransferase; LD24618p; LP11571p; Nucleolar protein 1; pantothenate kinase; RNA, U3 small nucleolar interacting protein 1; rRNA 2'-O-methyltransferase fibrillarin; U6 snRNA 2'-O-methyltransferase fibrillarin
基因别名: AL022665; CELE_T01C3.7; CG5725; Dmel\CG5725; Dmel_CG5725; dPANK; dPANK/Fbl; FBL; FIB; fib-1; FIB1; FLRN; PANK; RNU3IP1; T01C3.7
UniProt ID: (Human) P22087, (Rat) P22509, (Mouse) P35550, (C. elegans) Q22053
Entrez Gene ID: (Human) 2091, (Rat) 292747, (Mouse) 14113, (Fruit fly) 46234, (C. elegans) 179999
TFIID-class transcription factor binding
RNA binding
protein binding
rRNA methyltransferase activity
poly(A) RNA binding
ATPase binding
histone-glutamine methyltransferase activity
rRNA (adenine-N6,N6-)-dimethyltransferase activity
protein C-terminal carboxyl O-methyltransferase activity
tRNA (guanine-N2-)-methyltransferase activity
methyltransferase activity
C-methyltransferase activity
N-methyltransferase activity
O-methyltransferase activity
S-methyltransferase activity
RNA methyltransferase activity
mRNA methyltransferase activity
tRNA methyltransferase activity
protein methyltransferase activity
2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity
rRNA (uridine-2'-O-)-methyltransferase activity
rRNA (adenine-N6-)-methyltransferase activity
DNA-methyltransferase activity
tRNA (guanine-N1-)-methyltransferase activity
rRNA (cytosine-C5-)-methyltransferase activity
selenocysteine methyltransferase activity
arginine N-methyltransferase activity
protein-arginine N-methyltransferase activity
lysine N-methyltransferase activity
protein-lysine N-methyltransferase activity
tRNA (uracil) methyltransferase activity
tRNA (guanine) methyltransferase activity
tRNA (adenine) methyltransferase activity
tRNA (cytosine) methyltransferase activity
tRNA (cytosine-5-)-methyltransferase activity
tRNA (adenine-N1-)-methyltransferase activity
rRNA (adenine) methyltransferase activity
rRNA (cytosine) methyltransferase activity
rRNA (guanine) methyltransferase activity
rRNA (uridine) methyltransferase activity
transferase activity
protein C-terminal leucine carboxyl O-methyltransferase activity
1-phenanthrol methyltransferase activity
protein-arginine N5-methyltransferase activity
methylarsonite methyltransferase activity
dimethylarsinite methyltransferase activity
4,5-dihydroxybenzo(a)pyrene methyltransferase activity
1-hydroxypyrene methyltransferase activity
1-hydroxy-6-methoxypyrene methyltransferase activity
demethylmenaquinone methyltransferase activity
cobalt-precorrin-6B C5-methyltransferase activity
cobalt-precorrin-7 C15-methyltransferase activity
cobalt-precorrin-5B C1-methyltransferase activity
cobalt-precorrin-3 C17-methyltransferase activity
dimethylamine methyltransferase activity
hydroxyneurosporene-O-methyltransferase activity
tRNA (adenine-57, 58-N(1)-) methyltransferase activity
methylamine-specific methylcobalamin:coenzyme M methyltransferase activity
trimethylamine methyltransferase activity
methanol-specific methylcobalamin:coenzyme M methyltransferase activity
monomethylamine methyltransferase activity
P-methyltransferase activity
Se-methyltransferase activity
2-phytyl-1,4-naphthoquinone methyltransferase activity
tRNA (uracil-2'-O-)-methyltransferase activity
tRNA (cytosine-2'-O-)-methyltransferase activity
phosphomethylethanolamine N-methyltransferase activity
tRNA (cytosine-3-)-methyltransferase activity
rRNA (cytosine-2'-O-)-methyltransferase activity
rRNA (cytosine-N4-)-methyltransferase activity
trihydroxyferuloyl spermidine O-methyltransferase activity
pantothenate kinase activity
ATP binding
RNA processing factor
kinase
transferase
metabolite interconversion enzyme
box C/D snoRNA 3'-end processing
osteoblast differentiation
rRNA processing
tRNA processing
rRNA methylation
snoRNA localization
histone glutamine methylation
RNA processing
snoRNA metabolic process
methylation
mitotic cell cycle
response to oxidative stress
chromosome segregation
spermatogenesis
imaginal disc-derived wing morphogenesis
coenzyme A biosynthetic process
regulation of cytokinesis
locomotion
locomotor rhythm
oogenesis
meiotic cell cycle
membrane organization
triglyceride homeostasis
cellular response to gamma radiation
nucleologenesis
positive regulation of translation
